ACCM faculty members and trainees in Clinical Research have access to core facilities and support that serve as a comprehensive resource for planning, conducting, and analyzing data for research endeavors. Clinical Research is supported by research nurse coordinators, research coordinators, a biostatistician, and a database manager. Areas of active investigation span multiple perioperative disciplines including outcomes after cardiac surgery, pediatrics, critical care, and pain management. The research structure provides ample support for investigator and industry-supported studies, including database acquisition and access, administrative assistance and IRB submission support.
ACCM members click here to submit an application for CRC resources.
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Our Core Team
Melania Bembea, MD, MPH, PhD
Director of Anesthesiology and Critical Care Medicine Clinical and Translational Research
Professor, Department of Anesthesiology and Critical Care Medicine
Josh Rudnicki, MBA
Senior Research Program Manager
Department of Anesthesiology and Critical Care Medicine
Colleen Mennie
Senior Research Nurse
Department of Anesthesiology and Critical Care Medicine
Kamala Simkhada
Senior Research Nurse
Department of Anesthesiology and Critical Care Medicine
Beth White
Senior Research Nurse
Department of Anesthesiology and Critical Care Medicine
ACCM Featured Research
Our Researchers |
Featured Research |
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Ascenzi, Judy, DPN, RN Director, Johns Hopkins Children's Center of Pediatric Nursing Programs; Education, Informatics, and Research |
Implementation of a Bedside Checklist to Improve Neurologic Outcomes of Post-Cardiac Arrest Patients in a Pediatric Intensive Care Unit |
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Austin, Matt, PhD Associate Professor, Anesthesiology and Critical Care Medicine |
Further Maturation of a Partially-Developed Performance Measure of Stroke Misdiagnosis in Hospital Emergency Departments |
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Banks, Michael, MD, MEHP Assistant Professor, Anesthesiology and Critical Care Medicine |
Development of a New Inter-professional Education/Collaborative Practice Questionnaire.Development of a New Inter-professional Education/Collaborative Practice Questionnaire. |
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Barnes, Sean, MD, MBA Assistant Professor, Anesthesiology and Critical Care Medicine |
Association of Biomarkers and Postoperative Delirium in Children After Cardiac Bypass Surgery A Retrospective Analysis of Intraoperative Blood Glucose Levels and Monitoring Frequencies in Pediatric Patients Undergoing Cardiopulmonary Bypass Surgeries |
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Bembea, Melania, MD, PhD, MPH Director, ACCM Clinical Translational Research Program Professor, Anesthesiology and Critical Care Medicine |
Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation (BEAM) Immunology of Influenza Critical Illness in Young People (PICFLU2) |
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Booth, Lauren MSN, CRNP, PNP-AC Senior Nurse Practitioner Johns Hopkins Pediatric Intensive Care Unit (PICU) |
Improving Time to Antibiotic Administration in the Pediatric Intensive Care Unit |
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Chari, Asha, MD\ Clinical Associate, Anesthesiology and Critical Care Medicine |
Using Perioperative Code Simulation to Improve Teamwork |
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Chin, Laura, MD, MPH Assistant Professor, Anesthesiology and Critical Care Medicine |
Perspectives and barriers of Pediatric Anesthesiologists And Intensivists to learning point of care ultrasound (POCUS) |
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Chinedozi, Ima, MD, MPH Assistant Professor, Anesthesiology and Critical Care Medicine |
Competency and Optimization in Medical Oxygen Therapy (COMET-O2) |
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Cho, Brian, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
Discharge hemoglobin levels after cardiac surgery and 30-day readmission rates. Antithrombin-3 levels in multi-level spine surgeries and perioperative thrombotic events. |
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Cho, Sung-Min, DO, MHS Associate Professor, Anesthesiology and Critical Care Medicine – Neuroscience Critical Care |
SAfety and FEasibility of portable Magnetic Resonance Imaging in ECMO (SAFE MRI ECMO study) Assessing Acute Brain Injury after Rapid Reduction of PaCO2 upon ECMO Cannulation using Portable MRI and Biomarkers (DELTA ECMO ABI study) |
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Dalesio, Nick, MD Associate Professor, Anesthesiology and Critical Care Medicine – Otolaryngology-Head and Neck Surgery |
Using Machine Learning to Improve Accuracy in Allocating OR Block Time The Project SPRUCE Forest |
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Das, Sam, PhD Associate Professor, Anesthesiology and Critical Care Medicine – Pathology |
Exosome-based Non-traditional Technologies Towards Multi-Parametric and Integrated Approaches for SARS-CoV-2 |
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Dodd-o, Jeffrey, MD, PhD Associate Professor, Anesthesiology and Critical Care Medicine – Surgery |
Exploring an association between elastography and outcome following heart or liver procedures Evaluation of the Efficacy of CVSICU Protocol for Reversing Neuromuscular Blockade |
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Edwards, Lori-Ann, MBBS Assistant Program Director, Anesthesiology Residency Assistant Professor, Anesthesiology and Critical Care Medicine |
Quantitative Electromyography train-of-four monitoring in children: a pilot randomized controlled study |
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Engineer, Lilly, MD, DrPH Associate Director, Doctor of Public Health (DrPH) Program, Department of Health Policy and Management Assistant Professor, Anesthesiology and Critical Care Medicine |
The aim of this proposal is to measure the use of diabetes medications at specified time intervals before and after bariatric surgery. Johns Hopkins healthcare system Emergency Preparedness |
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Fackler, Jim, MD Professor, Anesthesiology and Critical Care Medicine |
Anesthesia and Critical Care Medicine Precision Medicine Analytical Platform (ACCM-PMAP) Pediatric Critical Care Data Collaborative: Multi-institutional De-identified Data Aggregation for Collaborative Analysis |
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Faraday, Nauder , MD, MPH Director, Perioperative Genomic and Translational Research, Perioperative Hemostasis and Thrombosis Research Professor, Anesthesiology and Critical Care Medicine |
Reducing readmission rates to surgical ICUs at Johns Hopkins Hospital Derivation of novel features from time series physiologic data to identify and predict risk of adverse outcomes in high risk surgical patients |
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Flavahan, Nicholas, PhD Professor, Anesthesiology and Critical Care Medicine |
Cutaneous vascular cell communication |
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Frank, Steven, MD Professor, Anesthesiology and Critical Care Medicine Chief of the Division of Adult Anesthesiology |
Intravenous Iron is Superior to Red Cell Transfusions for Preoperative Iron Deficiency Anemia: A Propensity Matched Cohort Study Database Review to Assess Blood and Blood Product Utilization at The Johns Hopkins Hospitals |
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Gao, Wei, MD Associate Professor, Anesthesiology and Critical Care Medicine |
Heart Failure with Preserved Ejection Fraction (HFpEF) Phenotypes and Postoperative Outcomes in Cardiac Surgery. |
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Geocadin, Romer, MD Professor, Anesthesiology and Critical Care Medicine – Neurology, Neurosurgery |
An Observational study of Somatosensory Evoked Potentials and Electroencephalography in Comatose Patients |
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Goeddel, Lee, MD, MPH, FCCM Associate Professor, Anesthesiology and Critical Care Medicine |
Pre-Operative AMPAC Score as a Predictor of Post-Operative Outcomes and Functional Capacity Association of left ventricular diastolic dysfunction to acute kidney injury after noncardiac surgery (DDAPKI study) |
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Goswami, Dheeraj, MD Director, Pediatric Cardiac Anesthesia Associate Professor, Anesthesiology and Critical Care Medicine |
Race and Its Effects on Perioperative Blood Transfusions for Pediatric Cardiac Surgery CHIlled Platelet Study (CHIPS) |
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Gurses, Ayse, PhD Director, Armstrong Inst. Center for Health Care Human Factors Professor, Anesthesiology and Critical Care Medicine |
Realtime Measurement of Situational Workload in NICU Clinicians to Improve Workload Management, Care Quality, and Patient Safety Patient-Centric Risk Model for Medication Safety During Care Transitions |
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Hensley, Nadia, MD Director ACCM Quality, Safety and Service Associate Professor, Anesthesiology and Critical Care Medicine |
Acute Normovolemic Hemodilution: A Prospective, Observational Study of the Volume Effect on Transfusions, Coagulation Mechanims and Safety Outcomes Perioperative Plasma in Addition to Red Blood Cell Transfusions are Associated with Increased Venous Thromboembolism Risk Postoperatively |
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Hoops, Katherine, MD, JD, MPH Associate Professor, Anesthesiology and Critical Care Medicine |
ACTFAST: Pediatric Trauma Centers RE-AIM at Gun Safety ACTFAST: Urban and Rural Trauma Centers RE-AIM at Firearm Safety |
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Horvath, Catherine, DNP, CRNA Program Director and Assistant Professor, Nurse Anesthesiology DNP Program | Effect of Resilience on Post Operative Pain in Geriatric Surgery Usability and Adoption of WikiAnesthesia with correlation to the Technology Acceptance Model |
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Hunsberger, Joann, MD, MS Assistant Professor, Anesthesiology and Critical Care Medicine |
Scoliosis Outcomes Database Registry Pediatric palliative medicine, pediatric acute pain medicine, and pediatric anesthesia involvement in end of life care |
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Hunt, Betsy, MD, MPH, PhD Co-Chair, Johns Hopkins CPR Advisory Committee Professor, Anesthesiology and Critical Care Medicine |
Personalizing Outcomes after Child Cardiac Arrest (POCCA) Resuscitation Smart Board |
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Johns, Roger, MD, MHS, PhD Professor, Anesthesiology and Critical Care Medicine |
DAMP Signaling Mediates HIMF-induced Pulmonary Hypertension |
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Kannan, Sujatha, MBBS Richard J. Traystman Endowed Chair Vice Chair for Research, Anesthesiology and Critical Care Medicine Professor, Anesthesia and Critical Care Medicine |
PediAtric ReseArch of Drugs, Immunoparalysis and Genetics during MODS (PARADIGM) Evaluation of the Kynurenine Pathway in Patients with Cerebral Palsy |
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Koka, Rahul, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
The role of a Telepresence Robotics Program as a form of distraction therapy in pediatric preoperative patients Society for Pediatric Anesthesia National Adverse Event Database |
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Kudchadkar, Sapna, MD, PhD Vice Chair, Pediatric ACCM Anesthesiologist-In-Chief Johns Hopkins Children's Center Director, Johns Hopkins PICU Up! Program Professor, Anesthesiology and Critical Care Medicine |
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children: A pragmatic, stepped-wedge trial Protein optimization with exercise to improve muscle mass and functional outcomes (PROXIMUS) trial |
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LaRosa, Jessica, MD Assistant, Professor Anesthesiology and Critical Care Medicine |
Evaluation of a Simulation Curriculum to Improve Frequency and Safety of Nursing-Led Early Physical Rehabilitation of Critically Ill Children A Quality Improvement Project to Standardize High Flow Nasal Cannula Weaning in Bronchiolitis in the Pediatric Intensive Care Unit |
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Laytin, Adam, MD, MPH Associate Professor, Anesthesiology and Critical Care Medicine – Emergency Medicine |
Qualitative Assessment of the Pilot Implementation of a Locally Adapted ICU Registry Protocol in Addis Ababa, Ethiopia Case mix, processes of care, adverse events and clinical outcomes of intensive care units in Addis Ababa, Ethiopia |
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Lee-Summers, Jennifer, MD Professor, Anesthesiology and Critical Care Medicine |
The JHU Visiting Professor Exchange Cerebrovascular Autoregulation in Children At Risk for Neurologic Injury |
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Lefebvre, Austen, MD Assistant Professor, Anesthesiology and Critical Care Medicine – Neurology |
Equivalency Comparison Between Non-Invasive Laser Optical Holography-Derived Scalp Measurement of Intracranial Pressure (ICP) & Invasive ICP Catheter Recordings in a Cohort of Moderate-Severe Brain-Injured ICU Patients. |
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Lester, Laeben, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
G-protein coupled sensory receptors in human heart and vascular tissue. A randomized controlled trial of an intervention to reduce the incidence of hypoxia with nasal CPAP versus standard care during procedural sedation for gastrointestinal endoscopy. |
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Levin, Amanda, MD Program Director, Pediatric Critical Care Medicine Fellowship Assistant Professor, Anesthesiology and Critical Care Medicine |
Evaluation of ATLS compliance and teamwork during in situ pediatric trauma activations and recorded alpha trauma activations. Effectiveness of Pediatric Trauma Boot Camp curriculum at improving confidence of clinical fellows with the care of pediatric trauma patients. |
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Mark, Lynette, MD Associate Professor, Anesthesiology and Critical Care Medicine Otolaryngology – Head and Neck Surgery |
Comparison of the educational effectiveness of DAARC, a video game-blended e-learning system, and traditional written materials: A pilot study (2021) |
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Mirski, Mark, MD, PhD |
Real-Time Screening for Pulmonary Infection with digitalMALDI Analysis Equivalency Comparison Between Non-Invasive Laser Optical Holography-Derived Scalp Measurement of Intracranial Pressure (ICP) & Invasive ICP Catheter Recordings in a Cohort of Moderate-Severe Brain-Injured ICU Patients. |
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Morad, Athir, MD Assistant Professor, Anesthesiology and Critical Care Medicine Neurology |
Post Craniotomy Analgesia Safety Monitoring with ET CO2 |
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Muehlschlegel, Danny, MD, MMsc, MBA, FASA, FAHA Director (Chair) of the Department of Anesthesiology and Critical Care Medicine Professor, Anesthesiology and Critical Care Medicine |
Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery TRanscriptomic ANalySis of left ventriCulaR gene Expression (TRANSCRibE) |
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Nguyen, Ed , MD Assistant Professor, Anesthesiology and Critical Care Medicine |
Trauma-Informed Anesthesia Care: Humanizing the Perioperative Process for Women with History of Sexual Assault Project GasCrowd: an online crowd-sourced, mobile-friendly database and communication tool for anesthesia practice guidelines |
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Noje, Corina, MD Co-Director JH Children's Center Pediatric Transport Program Associate Professor, Anesthesiology and Critical Care Medicine |
Interhospital Transport of Children with Aspirated Foreign Bodies: A Single-Center Experience Optimizing interfacility transport response time for pediatric out-of-hospital cardiac arrest: A quality improvement intervention |
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Nyquist, Paul, MD, FAHA, FCCM Professor,
Neurology
Anesthesiology and Critical Care Medicine Neurosurgery General Internal Medicine |
Cerebral regional oxygen saturation in sepsis using NIRS Continuous electro-encephalographic (cEEG) monitoring in the Intensive Care Unit: A survey of Intensive Care Units Worldwide |
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O'Brien, Caitlin, MD, MPH Associate Director, JH Pediatric Neurocritical Care Program Associate Professor, Anesthesiology and Critical Care Medicine |
Death One Hour After Terminal Extubation Study (DONATE) P-ICECAP: Pediatric Influence of Cooling duration on Efficacy in Cardiac Arrest Patients |
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O'Conor, Katie, MD Research Associate, Anesthesiology and Critical Care Medicine |
Trauma-Informed Care Education |
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O'Neil, Pooja, MD, MBA Program Director, Pediatric Anesthesia Fellowship Assistant Professor, Anesthesiology and Critical Care Medicine |
Chocolate or Sevoflurane? Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children |
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Phelps, Michael, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
Trends in ASATT exam participants and pass rates |
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Pustavoitau, Aliaksei, MD, MHS Associate Professor, Anesthesiology and Critical Care Medicine | Perioperative predictors of liver transplant mortality, morbidity and economic outcomes Incorporation of structured focused transthoracic echocardiography (FOTE) learning into an existing critical care fellowship training program: a prospective study. |
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Rivers, Richard, MD, PhD, MBA Associate Professor, Anesthesiology and Critical Care Medicine Ophthalmology |
The Pain Experience of Pediatric Obstructive Sleep Apnea Patients that have Undergone a Corrective Tonsillectomy and Adenoidectomy |
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Robertson, Courtney, MD Professor, Anesthesiology and Critical Care Medicine |
Improving Pediatric Traumatic Brain Injury Outcomes Through Equitable Care Implementation Neurologic Manifestations of COVID 19 in Children |
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Rollison, Sarah, DNP, CRNA Clinical Education Coordinator DNP Nurse Anesthesia track |
Utilizing Simulation to Promote Medication Preparation and Administration Safety in Anesthesia |
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Romer, Lewis, MD Professor, Anesthesiology and Critical Care Medicine Cell Biology Biomedical Engineering Pediatrics |
Kids MoD PAH Trial: Mono- vs. Duo-Therapy for Pediatric Pulmonary Arterial Hypertension Unsettling Situations in the Pediatric Intensive Care Unit: A Curriculum for Improving Resident Confidence and Competence When Negotiating Emotionally Challenging Encounters |
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Rosen, Michael, PhD Associate Professor, Anesthesiology and Critical Care Medicine |
Collective Allostatic Load: A Study of Stress, Teamwork, and Resilience in the PICU Modeling Intra-operative staff scheduling decision making |
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Rosenblatt, Kate, MD Assistant Professor, Anesthesiology and Critical Care Medicine Co-Director, Neurosurgical Anesthesia Fellowship Director of Outreach |
Noninvasive monitoring of cerebral autoregulation in sepsis using cerebral oximetry. |
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Santhanam, Lakshmi, PhD Associate Professor, Anesthesiology and Critical Care Medicine |
Examining role of H2S producing enzymes in human microvascular function |
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Scafidi, Susanna, MD Associate Professor, Anesthesiology and Critical Care Medicine |
Clinical practice in management of seizures in pediatric abusive head trauma Retrospective review of clinical characteristics, management and outcomes of Pediatric patients with cerebral vasospasm |
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Schiavi, Adam, MD, PhD, MS Associate Professor, Anesthesiology and Critical Care Medicine Neurology |
Center for Immersive Simulation and Telemedicine (CISTEL) anesthesiology resident simulation training program |
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Schramm, Jenny, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
Machine learning to identify risk factors for the development of necrotizing enterocolitis in children with congenital heart disease Collaborative Research with Pediatric Cardiac Intensive Care Society (CoRe-PCICS) I: Hyperoxia during CPB in Neonates |
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Schwengel, Deborah, MD Associate Professor, Anesthesiology and Critical Care Medicine |
mHealth Platform for the dissemination of vetted clinical medical knowledge to health professionals: A multi-center usability study The Development and Validation of a Procedural Checklist for aSimulation-Based Mastery Learning Curriculum for Ultrasound-Guided Interscalene Peripheral Nerve Blocks |
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Segna, Kara, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
The impact of a multi-disciplinary pain medicine curriculum on attitudes surrounding pain and opioids |
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Shah, Vishank, MD Assistant Professor, Anesthesiology and Critical Care Medicine Neurology |
A Retrospective evaluation of the relationship between Intracranial pressure dynamics and Near-Infrared Spectroscopy (NIRS) signals in patients with aneurysmal subarachnoid hemorrhage admitted to the Neurocritical Care Unit |
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Shechter, Ronen, MD Assistant Professor, Anesthesiology and Critical Care Medicine Pain Medicine |
Perioperative Pain Program (PPP) role in minimizing opioid utilization, decreasing length of stay and improving clinical outcome measured using validated surveys in "opioid dependent" surgical patient population (ODSP). |
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Sieber, Frederick, MD Professor, Anesthesiology and Critical Care Medicine |
RESTORE (RESilience in TOtal knee REplacement) v |
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Shilkofski, Nicole, MD, MED Vice Chair of Education, Department of Pediatrics Residency Program Director, Pediatrics Associate Professor of Pediatrics |
Design, Implementation and Evaluation of a Simulation-Based Peer to Peer Educational Intervention in Pediatric Resuscitation in Myanmar and Uganda Dissemination and Impact of Integrated Simulation Training in "Helping Babies Breathe" and "Helping Mothers Survive" Programs in the Philippines |
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Sivanesan, Eellan, MD, FASA Director of Neuromodulation Associate Professor, Anesthesiology and Critical Care Medicine |
Reuse of explanted spinal cord stimulators in rodents for the study of chronic pain Identification of Pain Related Genes and Neurochemical Changes in Dorsal Root Ganglion |
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Smith Stierer, Tracey, MD Associate Professor, Anesthesiology and Critical Care Medicine Otolaryngology-Head and Neck Cancer |
Multicenter Perioperative Outcomes Group (MPOG) and Anesthesiology Performance Improvement and Reporting Exchange (ASPIRE) Performance Site |
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Steppan, Diana, MD, MPH Assistant Professor, Anesthesiology and Critical Care Medicine |
Multicenter Retrospective Review of BAL in Pediatric HSCT patients |
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Steppan, Jochen, MD, DESA, FAHA, FASA Director of Perioperative Medicine Associate Professor, Anesthesiology and Critical Care Medicine |
Operating room procedures for high risk patients with pulmonary hypertension. LOXL2 in pulmonary hypertension |
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Stevens, Robert, MD, MBA, FCCM Director,
Division of Informatics, Integration, and Innovation, ACCM Precision Medicine Associate Director, Precision Medicine Center of Excellence Associate Professor, Anesthesiology and Critical Care Medicine |
Physiological waveform analysis for clinical prediction in the intensive care unit Bridge2AI: A Patient-Focused Collaborative Hospital Repository Uniting Standards (CHoRUS) for Equitable AI |
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Stockwell, David, MD, MBA Chief Medical Officer, John's Hopkins Children's Center Associate Professor, Anesthesiology and Critical Care Medicine |
Disparities in Voluntary Event Reporting within an Academic Health System Epidemiology of Pediatric Intensive Care Patients using the Pediatric Health Information System Database |
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Suarez, Jose, MD, FNCS, FANA, FAAN Professor and Chief, Neurosciences Critical Care Director, Precision Medicine Center of Excellence for Neurocritical Care Professor, Anesthesiology and Critical Care Medicine, Neurology, and Neurosurgery |
Physiologic Data Capture and Analysis in the Neuroscience Critical Care Unit The Johns Hopkins Precision Medicine Center of Excellence in Neurocritical Care |
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Suffredini, Giancarlo, MD Assistant Professor, Anesthesiology and Critical Care Medicine |
Evaluating the relationship between liver stiffness as obtained by 2D-Shear Wave Elastography and illness severity in patients with COVID-19. |
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Toy, Serkan, PhD, Med Assistant Professor, Anesthesiology and Critical Care Medicine |
Using Electroencephalography to Measure Neurocognitive Engagement and Cognitive Load During Procedural and Clinical Decision-making Tasks |
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Tran, Tina, MD Chief of Anesthesia at the Wilmer Eye Institute Assistant Professor, Anesthesiology and Critical Care Medicine |
Improved Cable Management System for Anesthesia Monitoring Devices Used in Surgical and Critical Care Settings Developing a 4 Week Learner-Focused Anesthesia Clerkship Curriculum to Promote Medical Student Active Learning in the Clerkship Setting |
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Vanderhoek, Samuel, MD Associate Professor, Anesthesiology and Critical Care Medicine |
Patterns and Practices of Perioperative Insulin Pump Management in Children with Diabetes Understanding Provider Practices in Pediatric Ambulatory Anesthesia |
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Vecchione, Tricia, MD Associate Professor, Anesthesiology and Critical Care Medicine |
Trajectories of Pediatric Patients With Acute Compartment Syndrome or Limb Ischemia Associated With Peripheral Nerve Blocks |
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Winters, Bradford, PhD, MD, FCCM Division Director,
Adult Critical Care Medicine Co-Director, JHH Surgical ICUs, Bayview Medical Center and Burn ICUs, Armstrong Inst. For Patient Safety and Quality Professor, Anesthesiology and Critical Care Medicine Surgery |
CUSP for Diagnostic Accuracy and Antibiotic Stewardship in Telemedicine v |
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Wolpaw, Jed, MD, M.Ed Professor Anesthesiology and Critical Care Medicine Residency Program Director |
Examining the interplay between physical activity, sleep, work schedule, and burn-out in anesthesiology residents Unconscious Bias In Anesthesia Residency Applicant Letters of Recommendation |
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XIE, Anping, PhD Associate Professor Anesthesiology and Critical Care Medicine |
Evaluation of an Intervention for Improving Patient Engagement in Perioperative Pain Management Strategies for Improving Prescription Opioid Use in Perioperative Pain Management |
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Ziai, Wendy, MD, MPH Assistant Professor Anesthesia and Critical Care Medicine Neurology, and Neurosurgery |
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) Phase 2a trial |