Thank you to everyone who joined us for Research Day, as well as each of the moderators and presenters who helped to make the evening possible.
ACCM Research Day is an exceptional forum to share insights and innovative research from the past year. Gathering the brilliant minds of the Johns Hopkins ACCM family in one location catalyzes creative thinking, fosters collaboration, and fuels innovation. Together, we aim to fulfill the ACCM mission of becoming a global leader in discovery, innovation, education, and professional development.
We encourage participants at all levels of their learning journey to share in the rich resources of the ACCM community, engage in multidisciplinary projects, initiate research collaborations, and seek out mentorship in the department. The scientific program will be organized in different sessions, providing the latest updates and showcasing the most promising research in the field of anesthesiology and critical care medicine. Our research will be presented in the categories: Basic Science: Cardiovascular & Pulmonary; Basic Neuroscience; Clinical Research; Critical Care; Informatics, AI, Engineering, & Technology; Pain & Regional Anesthesiology; and Quality Improvement & Health Systems/Services.
VISITING PROFESSOR & KEYNOTE SPEAKER
“AI in Critical Care: the Potential for Enhancing Patient Safety and Outcomes”
Dr. Gari Clifford, DPhil
Chair & Professor, Department of Biomedical Informatics, Emory University School of Medicine
Professor, Department of Biomedical Engineering, Georgia Institute of Technology
Originally trained in theoretical physics, Dr. Clifford’s research focuses on the application of signal processing, machine learning, and physiological modeling to low-cost sensors to classify, track, and predict health and illness. In 2023, he was elected a fellow of the Institute of Electrical and Electronic Engineers for his work in AI in Cardiology. He is also well known for his work in critical care (particularly for managing the construction and deployment of the MIMIC II database) and for translational research in fetal monitoring.
Dr. Clifford has spent much of the last decade developing programs focused on mental health and neurological diseases. While on faculty at the University of Oxford, he co-founded the Sleep and Circadian Neuroscience Institute, focusing on sleep and mental health. He also founded the Center for Affordable Healthcare Technology there, which led to the Co-Design Lab For Health Equity and Safe+Natal, both now run out of Emory. Through these initiatives, he is committed to addressing health equity and developing sustainable solutions to healthcare problems in resource-poor locations, with much of his work focused in Central America. Dr. Clifford is also a champion of Open Access data and Open Source software, particularly through his leadership of the PhysioNet/CinC Challenges and contributions to the PhysioNet Resource over the last two decades.
Click to view the 2024 ACCM Research Day Book (JHED ID required)
26th Annual ACCM Research Day Award Recipients
Basic Science: Cardiovascular & Pulmonary
1st: Travis Brady BS, BA
Evolution of cell-ECM crosstalk and biomechanics during arterial aging
2nd: Marta Martinez Yus BS
Menopause accelerates arterial stiffening via VSMC dysfunction and ECM remodeling
Basic Neuroscience 1
1st: Lakshmi Valliyappan
Ketamine-conjugated PAMAM hydroxyl dendrimer rescues depressive-like symptoms in a rat model of rotenone-induced Parkinson’s disease
2nd: Javier Allende Labastida MD, PhD, MPH
Novel juvenile rabbit model of diffuse axonal injury using the CHIMERA traumatic brain injury model shows developmental delays
Basic Neuroscience 2
1st: Preeti Vyas MPharm, PhD
Glucose dendrimer-ketamine targets hyperactive neurons and protects against seizures in a rodent model of Status epilepticus
2nd: Qihong Wang MD
Laser speckle contrast imaging (LSCI) application in a neonatal pig middle cerebral artery occlusion (MCAO) model
Clinical Research 1
1st: Jessica Asiedu BS
Variation in platelet transfusion triggers by physician and department in surgical patients
2nd: Ryan Nicholson MPH
Is all iron created equal: a retrospective cohort analysis of postoperative outcomes associated with intravenous iron formulations
Clinical Research 2
1st: Joann Hunsberger MD, MS
A single institution’s perioperative management of cloacal exstrophy
2nd: Gifty Agyemang BA, MD
Is anesthesiology universal? A qualitative comparison of anesthetic techniques in Ghana, The Gambia, and the United States of America
Critical Care 1
1st: Winnie Liu BS
Ableist language in goals of care discussions in the neurocritical care unit
2nd: Phillip Cohen MD, MSc
Neonatologist perspectives on non-emergent NICU to PICU transfers
Critical Care 2
1st: Emily Kemper MD
Communication experiences among low-income families in the pediatric ICU: a qualitative study
2nd: Lauren Booth MSN
New diagnostic stewardship tool for pediatric critical care reduces disparity
Informatics, AI, Engineering, & Technology
1st: Chris Acha BS Cellular biosensors in microtubes
2nd (tied): Ananya Tandri MS, BS
Novel ultrasound monitoring of shunt-implanted hydrocephalus patients for early detection of bacterial meningitis
2nd (tied): Roscoe Bratton MD
Using machine learning (ML) to improve accuracy in allocation of operating room block time
Pain & Regional Anesthesiology
1st: Ankit Uniyal PhD
Positive allosteric modulation of human Mas-related G protein-coupled receptor X1 as novel therapeutics for the treatment of neuropathic pain
2nd: Winnie Liu BS
Examining pre-delivery healthcare spending and service utilization among individuals with opioid use disorder during pregnancy
Quality Improvement & Health Systems/Services
1st: Lori-Ann M. Edwards MBBS
Implementation of universal quantitative neuromuscular blockade monitoring in an academic pediatric center
2nd: Kristen Joseph MD
Lesotho national oxygen dashboard for real-time monitoring and forecasting of hospital oxygen supply and demand
Health Equity
1st: Winnie Liu BS
Ableist language in goals of care discussions in the neurocritical care unit
2nd: Lauren Booth MSN
New diagnostic stewardship tool for pediatric critical care reduces disparity
Health Equity Honors
The Health Equity Honors program highlights research that advances our departmental and institutional commitment to health equity. We believe that research in every domain of scientific discovery is crucial for advancing health equity in clinical care and outcomes.
Understanding the mechanisms of disparity informs our collective ability to design healthcare that serves the unique needs of every patient. Submissions were selected for this honor if they explored any aspect of health equity, including:
- Characterizing mechanisms of disparity
- Investigating populations associated with inequities
- Evaluating interventions aimed at promoting equity / addressing disparities
- Advancing educational programs to disseminate information on equity You can find these in the schedule with a HE designation.
2024 Health Equity Honorees
Ableist language in goals of care discussions in the neurocritical care unit (Critical Care 1)
Winnie L. Liu BS, Caroline Cerilli BA, Lourdes Carhuapoma PhD CRNP, Bonnielin K. Swenor PhD MPH, Susanne Muehlschlegel MD MPH
Associations of mild behavioral impairment domains with brain volumes in older adults (Clinical Research 2)
Lisa Young BS BA, Lisa N. Richey BA, Connor A. Law BS, Aaron I. Esagoff BS, Zahinoor Ismail MD, Matthew L. Senjem MS, Clifford R. Jack Jr. MD, Srishti Shrestha PhD, Rebecca F. Gottesman MD PhD, Khaled Moussawi MD, PhD, Matthew E. Peters MD, Andrea L.C. Schneider MD PhD
Communication experiences among low-income families in the pediatric ICU: a qualitative study (Critical Care 2)
Emily Kemper MD, Michelle Eakin PhD, Sapna R. Kudchadkar MD PhD
Dendrimer-Tesaglitazar therapy ameliorates obesity and atherosclerosis in both male and female ApoE knockout mice (Basic Science: Cardiovascular & Pulmonary)
Diego Almodiel BS, Wathsala Liyanage PhD, Javier Allende Labastida MD PhD, Travis Brady BS, Saanvi Sudhir, AJ Hernandez, Mahin Gadkari MSE, Marta Martinez Yus BS, Kannan Rangaramanujam PhD, Sujatha Kannan MD, Lakshmi Santhanam PhD
Deriving a context-appropriate ventilator-associated pneumonia bundle for Ethiopia (Critical Care 1)
Desalegn Keney MD MPH, Menbeu Sultan MD MPH, Ephrem Hassan RN, Bhakti Hansoti MBChB MPH PhD, Adam D. Laytin MD MPH
DURABLE: dual HRV and blood pressure assessment for neurological evaluation (Clinical Research 1)
Prachi Agarwal PhD, Mingfeng Cao MS, Yu Guo PhD, Payam Gharibani PhD, Romergryko Geocadin MD PhD, Nitish Thakor PhD
Enhancing oxygen therapy in Sub-Saharan Africa: implementation and evaluation of the DIMAHP curriculum (Critical Care 2)
Nivedita Kumar BS, Ima Chinedozi MD MPH, Ifeanyi Chinedozi MD MBA, Reade Tillman MD, Gaurav Shreshtra MD, Gifty Agyemang MD, Oluchi Ogbonna BS, Ifeoma Ekwere MD, Michael Banks MD, Folayemi Faponle MD, Uchechukwu Agwu MD, Oluwakemi Tomobi MD, Victoria Alex MD, Dawda Jammeh NP, Antouman Jagne NP, Sulayman Jallow NP, Isatou Camara NP, John Sampson MD
Examining pre-delivery healthcare spending and service utilization among individuals with opioid use disorder during pregnancy (Pain & Regional Anesthesiology)
Winnie L. Liu BS, Anjali A. Dixit MD MPH, Katie J. O’Conor MD MBA, Eric C. Sun MD PhD
Impact of solar-power and oxygen generation systems on mortality and patient outcomes in low-resource hospitals: a prospective cohort study in Gambia (Critical Care 2)
Tsegaye Hundie MD MPH ScM, Nivedita Kumar BS, Folayemi Faponle MD, Antouman Jagne RN, Sabina Kangakan MD, Joy Akinjide BS, Ifeanyi Chinedozi MD MBS, Ima Chinedozi MD MPH, John Sampson MD
Implementing universal firearm injury prevention intervention across pediatric trauma centers: a type II hybrid implementation-effectiveness study (Quality Improvement & Health Systems/Services)
Natasha Houshmand MD, Anna DuVal BA MPH, Katherine Hoops MD MPH
Interfacility transport response time for pediatric out-of-hospital cardiac arrest: can we do better? (Quality Improvement & Health Systems/Services)
Bridget Devlin RN, Lauren Harkins RN, Philomena Costabile RN, Bruce Klein MD, Matthew J. Levy DO, Corina Noje MD
Investigating the cellular origin of brain-derived extracellular vesicles in a pediatric rabbit model of tuberculous meningitis (Basic Neuroscience 2)
Nicole Beaubien, Daisy Puca, Blanca V. Rodriguez PhD, Nelly Damiba, Samarjit Das PhD, Elizabeth W. Tucker MD
Is anesthesiology universal? A qualitative comparison of anesthetic techniques in Ghana, The Gambia, and the United States of America (Clinical Research 2)
Gifty Agyemang MD, Ima Chinedozi MD MPH, John Sampson MD
Laser speckle contrast imaging (LSCI) application in a neonatal pig middle cerebral artery occlusion (MCAO) model (Basic Neuroscience 2)
Qihong Wang MD, Mostafa Abdulrahim MD, Larraine Lage LVT, Risheng Xu MD PhD, Emmett Whitaker MD
Lesotho national oxygen dashboard for real-time monitoring and forecasting of hospital oxygen supply and demand (Quality Improvement & Health Systems/Services)
Kristen S. Joseph MD, Tspeo Ntelane, Tiiso D. Lekhela MD, Sello Montsi, Sebaki F. Leluma, Bhakti Hansoti MD PhD, Nicole Shilkofski MD MEd, Eric D. McCollum MD MPH
Menopause accelerates arterial stiffening via VSMC dysfunction and ECM remodeling (Basic Science: Cardiovascular & Pulmonary)
Marta Martinez Yus BS, Travis Brady BS, Diego Almodiel BS, Mahin Gadkari MSE, Kavitha Nandakumar, Lakshmi Santhanam PhD
Methods of evidence-sharing used by clinicians in prognostication meetings for critically ill neurologic patients (Critical Care 1)
Mahimasri Kotamreddy BS, Brooke Honzel BS, Raphael Carandang MD, Susanne Muehlschlegel MD MPH
New diagnostic stewardship tool for pediatric critical care reduces disparity (Critical Care 2) Lauren D. Booth MSN CRNP, Matt Linz MD, Aaron Milstone MD MHS, David Stockwell MD, Christina Schumacher PhD MHS, Anna Sick-Samuels MD MHS
Novel ultrasound monitoring of shunt-implanted hydrocephalus patients for early detection of bacterial meningitis (Informatics, AI, Engineering, & Technology)
Ananya Tandri, Yiyang You, Joseph Dardick MD, Mark Luciano MD PhD, Jeeun Kang PhD
Oxygen for moderately hypoxemic children in Malawi: NoGoLO2 pilot randomized controlled trial (Quality Improvement & Health Systems/Services)
Kristen S. Joseph MD, Tisungane Mvalo MD, Holly B. Schuh PhD MPH, Carina King MD, Tim Colbourn MD, Shubhada Hooli MD MPH, Heather J. Zar MD PhD, Stephen R.C. Howie PhD, Nicole Shilkofski MD MEd, Eric D. McCollum MD MPH
Post-traumatic depression presents with anhedonia-like behavior in adult rats following repetitive traumatic brain injury (Basic Neuroscience 2)
Varsha Arun, Javier Allende Labastida MD PhD MPH, Maria Paula Avalos PhD, Preeti Vyas MPharma PhD, Mytreyi Trivedi, Jinhuan Liu BSN, Raymond C. Koehler PhD, Sujatha Kannan MD
RatCHIMERA TBI model induces post-traumatic depression presenting with learned helplessness (Basic Neuroscience 1)
Mytreyi Trivedi, Javier Allende Labastida MD PhD MPH, Maria Paula Avalos PhD, Preeti Vyas MPharm PhD, Varsha Arun, Jinhuan Liu BSN, Raymond C. Koehler PhD, Sujatha Kannan MBBS
Securing access, accountability and sustainability of medical oxygen production in The Gambia: a failure modes and root cause analysis of PSA oxygen supply systems serving the Edward Francis Small Teaching Hospital (Quality Improvement & Health Systems/Services)
Ryan Alezz, Samson Jarso PhD, Kim Hwang Yeo, Dawda Cham, Michael Rosen PhD, Ifeoma Ekwere MD, Selam Degu MD, John B. Sampson MD
Sex-specific variations in vascular properties across pulmonary and systemic circulations (Basic Science: Cardiovascular & Pulmonary)
Mahin Gadkari MSE, Marta Martinez Yus BS, Diego Almodiel BS, Travis Brady BS, Phillip Azarcón BS, Karthik Suresh MD, Lakshmi Santhanam PhD
Sphenopalatine ganglion block as a novel approach to post-dural puncture headache (Pain & Regional Anesthesiology)
Anthony Bishara BA, Omar Singer MD, Mina Gaballa DO
Targeting LOXL2 against arterial stiffening in post-menopausal females (Basic Science: Cardiovascular & Pulmonary)
Marta Martinez Yus BS, Kavitha Nandakumar, Lakshmi Santhanam PhD
The impact of sevoflurane on cerebral autoregulation in adult offspring of preeclamptic pregnancies (Basic Neuroscience 1)
Navid Modiri MD, Tre Diemer BS, Sanaz Nasoohi PhD, Qihong Wang MD, Emmett Whitaker MD
ACCM RESEARCH DAY 2024 THANKS YOU
We express our gratitude to all the researchers, especially trainees, who made this day possible by sharing their work and the principal investigators for their encouragement and unconditional support. We greatly appreciate Dr. Sujatha Kannan and Dr. Melania Bembea for their leadership, and Dr. Katie O’Conor, Sarah Danihel, Brittni Delmaine, Kayla Singer, and our lead Research Ambassador, Lauren Tirado, for organizing this wonderful event. Lastly, our sincere thanks to our ACCM Director, Dr. Jochen Daniel Muehlschlegel and his office for their enthusiastic support and investment in departmental resources, allowing us to consistently lead the world in discovery and innovation. ACCM Research Day would not be possible without your collective contributions.
Best Regards,
Jennifer Schramm, MD
ACCM Research Day Faculty Host
Assistant Professor
Division of Pediatric Cardiac Critical Care
Ima Chinedozi, MD
ACCM Research Day Faculty Host
Assistant Professor
Divisions of Cardiac Anesthesiology & Critical Care
Katie J. O’Conor, MD MBA
ACCM Research Day Faculty Lead
ACCM Chief Diversity & Equity Officer
ACCM Director of Data Science (MPOG)
Anesthesiology and Critical Care Medicine
Johns Hopkins University School of Medicine