GRANTS RECEIVED
Please join us in congratulating the most recent recipients of the ACCM StAAR awards!
Dr. Samarjit Das received a StAAR Investigator Award for the project “A Cross-talk Between Heart and Skeletal Muscle During the Pathogenesis of Heart Failure.” His collaborators for this project are Robert Weiss (Cardiology) and Erick Hernández-Ochoa (University of Maryland School of Medicine, Biochemistry and Molecular Biology).
Dr. Nicola Heller received a StAAR Investigator Award for the project “Immune Changes After Cardiac Surgery and Postoperative Neurocognitive Dysfunction.” Her collaborator for this project is Dr. Charles Brown.
Dr. Adam Laytin received a StAAR Transformative Award for the project “Pilot Implementation and Dissemination of a Context-Appropriate Ventilator-Associated Pneumonia Prevention Bundle in Ethiopia.” His collaborators for this project are Dr. Sapna Kudchadkar, Dr. Bhakti Hansoti (Emergency Medicine), and Dr. William Checkley (Pulmonology/Critical Care Medicine).
Dr. Rohan Mathur received a StAAR Investigator Award for the project “Developing Novel Similarity Mapping Metrics And Visualization Tool to Identify and Visualize Dynamic Endotypes and Cohorts of Patients with Aneurysmal Subarachnoid Hemorrhage.” His collaborators for Peter Dziedzic, Niteesh Potu, Lin Cheng, Eusebia Calvillo, Jose Suarez from the NCCU with collaborators from the Whiting School of Engineering.
Dr. Susanne Muehlschlegel received a StAAR Investigator Award for the project “Pilot Trial of a Digital Web/Mobile/Tablet-Based Goals of Care Decision Aid to Promote Shared Decision Making Between Clinicians and Families in the NeuroICU.” Her collaborator for this project is Dr. Jamie Perin (BEAD core).
Dr. Jennifer Schramm received a StAAR Mentored Award for the project “Machine Learning to Identify Risk Factors for the Development of Necrotizing Enterocolitis in Children with Congenital Heart Disease.” Her mentors and collaborators for this project are Dr. Allen Everett (Pedriatrics), Dr. Melania Bembea, and Dr. Cedric Manlhiot (Director, Cardiovascular Analytic Intelligence Initiative).
Dr. Vishank A. Shah received a StAAR Mentored Award for the project “Individualization of Arterial Blood Pressure Targets in Aneurysmal Subarachnoid Hemorrhage Using Non-invasive Multimodal Monitoring.” His mentor for this project is Dr. Jose Suarez.
ACCOMPLISHMENTS AND HONORS
Promotions and Appointments
Vahid Grami, MD, MPH, has joined the department as an Assistant Professor and the Program Director for the Anesthesiology Pain Medicine Fellowship as of July 1st.
Adam Laytin, MD, MPH, was appointed an Honorary Assistant Professor at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia, in the Department of Intensive Care Medicine.
Pooja O’Neil, MD, MBA, has been appointed Program Director for our Johns Hopkins Pediatric Anesthesiology Fellowship.
Emmet Whitaker, MD, FAAP, is stepping into the role of Associate Program Director.
Other Accomplishments and Honors
Please join us in congratulating David Berman, MD, MEHP, for finishing his Masters in Education in the Health Professions (MEHP) at Johns Hopkins!
Sung-Min Cho, DO, MHS, gave a talk entitled “ELSO Guidelines on Neurological Monitoring and Management of ECMO” at the Korea Hospital Cardiac Surgery Grand Rounds in Seoul, South Korea in June 2024. Dr Cho also gave 3 presentations at the Asia Pacific Neurocritical Care Conference in Kuching Sarawak, Malaysia in June 2024. His talks were entitled “Neuroprognostication in Comatose Adult Survivors of Cardiac Arrest”, “Neurocritical Care of ECMO – ELSO Guideline”, and “Neuromonitoring of ECMO”. In July 2024, Dr Cho gave a talk entitled “Neurocritical Care of ECMO – ELSO Guidelines on Neurological Monitoring and Management of ECMO” at the Samsung Medical Center Critical Care Grand Rounds in Seoul, South Korea.
Steve Frank, MD, and colleagues were featured in a Johns Hopkins Medicine Newsroom press release for their recent article “A propensity-matched cohort study of intravenous iron versus red cell transfusions for preoperative iron-deficiency anemia”, which was recently published in Anesthesia & Analgesia. The full press release can be found on the Newsroom website.
Anita Gupta, DO, MPP, PharmD, FASA, will be speaking at the California Physicians Medical Association on Women’s Health in Monterey, CA. Her presentation is entitled “Women’s Pain Matters: Expert Insights & Best Practices” and will be delivered on September 7, 2024. Dr Gupta also published a WebMD Expert Blog on managing chronic pain.
An article published by Nadia Hensley and colleagues in Anesthesia & Analgesia was selected as the front cover as the featured article for August 2024, “Perioperative plasma in addition to red blood cell transfusions are associated with increased venous thromboembolism risk postoperatively”. Dr Hensley was also interviewed by the editor of Anesthesia & Analgesia for a podcast on the featured article for August 2024.
Adam Laytin, MD, MPH, is co-directing the International Lecture Series for African Critical Care Fellows with intensivists from Ethiopia and Ghana through the JHU World Health Organization Collaborating Center for Emergency, Critical and Operative Care, which launched this month.
Rohan Mathur, MD, MPA, gave Combined Critical Care Grand Rounds at the University of Iowa Carver College of Medicine on “Evolving Concepts in Intracranial Pressure Management”. Dr Mathur also gave a keynote talk entitled “The Future of Stroke Care: The Revolutionary Potential of AI, Machine Learning and Brain Computer Interfaces” at the Stanley Wissman Stroke Symposium in Fort Wayne, IN, in May 2024.
Susanne Muehlschlegel, MD, MPH, FNCS, FCCM, FAAN, was interviewed by the American Academy of Neurology Continuum about her recent review article entitled “Prognostication in neurocritical care”. The interview can be found on the Continuum website. Dr Muehlschlegel was also invited to submit a full proposal to the Donaghue Foundation for her project “Impact of a shared decision-making intervention for families of severe acute brain injury patients”.
CORRECTION: In last month’s email, it was reported that Daniel Nyhan traveled to Tanzania. It was Aoibhinn Nyhan, MD, and Rob Greenberg, MD, who traveled to Bugando Medical Center, Mwanza, Tanzania (May 18-26) to provide expert clinical care to both children and adults undergoing facial plastic surgery as part of an ongoing program with Healing the Children, Northeast. In addition to clinical care they both provided educational lectures and intraoperative teaching with the anesthesia clinicians. Dr Aoibhinn Nyhan’s presence was invaluable!
Katie O’Conor MD MBA was a collaborator and co-author on the invited presentation, “Colocating Syringe Services, COVID-19 Vaccination, and Infectious Disease Testing: Baltimore’s Experience” at the Health Affairs Reimagining Public Health Special Issue Panel in June, along with colleagues Heidari O (lead), Meyer D, Lowensen K, Patil A, LaRicci J, Hunt D, Bocek AP, Cargill V, and Farley JE.
John B. Sampson, MD, was featured on Gambia Radio and Television Services for his work on developing an oxygen-generating plant at the Edward Francis Small Teaching Hospital. Gambian officials, including the Minister of Health and the First Lady, discussed the impact this Society of Critical Care Medicine-sponsored project has on the delivery of medical care in The Gambia. The video recording of the broadcast can be found on YouTube. Dr Sampson’s work across Ghana, The Gambia, Liberia, and Sierra Leone was highlighted by the Society of Critical Care Medicine Podcast this month. Dr Sampson also was part of an expert panel for the Coalition for Universities of Global Health (CUGH) on “The Argument for Equitable Care: A Conversation with Champions and Experts”, which can be found on YouTube.
ARTICLES PUBLISHED
Basic and Translational Research
Bakare AO, Stephens K, Sanchez KR, Liu V, Zheng L, Goel V, Guan Y, Sivanesan E. Spinal cord stimulation attenuates paclitaxel-induced gait impairment and mechanical hypersensitivity via peripheral neuroprotective mechanisms in tumor-bearing rats. Reg Anesth Pain Med. Published online June 14, 2024. doi:10.1136/rapm-2024-105433
Bruzek S, Betensky M, Sochet AA, Goldenberg NA, Ignjatovic V. Methods, precision, and analytical sensitivity of a novel low-plasma-volume assay of fibrinolytic capacity utilizing the euglobulin fraction. Int J Lab Hematol. 2024 Jul 9. doi: 10.1111/ijlh.14340. Epub ahead of print.
He X, Long Q, Zhong Y, Zhang Y, Qian B, Huang S, Chang L, Qi Z, Li L, Wang X, Yang X, Dong Gao W, Ye X, Zhao Q. Short-chain fatty acids regulate erastin-induced cardiomyocyte ferroptosis and ferroptosis-related genes. Front Pharmacol. 2024 Jul 12;15:1409321. doi: 10.3389/fphar.2024.1409321
Khoury ES, Patel RV, O’Ferrall C, Fowler A, Sah N, Sharma A, Gupta S, Scafidi S, Kurtz JS, Olmstead SJ, Kudchadkar SR, Kannan RM, Blue ME, Kannan S. Dendrimer nanotherapy targeting of glial dysfunction improves inflammation and neurobehavioral phenotype in adult female Mecp2-heterozygous mouse model of Rett syndrome. J Neurochem. 2024;168(5):841-854. doi:10.1111/jnc.15960
Ma Z, Liu T, Liu L, Pei Y, Wang T, Wang Z, Guan Y, Zhang X, Zhang Y, Chen X. Epidermal neural crest stem cell conditioned medium enhances spinal cord injury recovery via PI3K/AKT-mediated neuronal apoptosis suppression. Neurochem Res. 2024 Jul 18. doi: 10.1007/s11064-024-04207-8. Epub ahead of print.
Sorcher JL, Santos PT, Adams S, Kulikowicz E, Vaidya D, Lee JK, Hunt EA, Koehler RC, Shaffner DH, O’Brien CE. Association of diastolic blood pressure with coronary perfusion pressure during resuscitation in pediatric swine. Pediatr Res. 2024 Jul 15. doi: 10.1038/s41390-024-03308-y. Epub ahead of print.
Wang H, Martinez Yus M, Brady T, Choi R, Nandakumar K, Smith L, Jang R, Wodu BP, Almodiel D, Stoddart L, Kim DH, Steppan J, Santhanam L. Sex differences and role of lysyl oxidase like 2 (LOXL2) in Angiotensin II-induced hypertension in mice. Am J Physiol Heart Circ Physiol. 2024 Jul 19. doi: 10.1152/ajpheart.00110.2024. Epub ahead of print.
Clinical Research
Ahmad SA, Kapoor S, Muquit S, Gusdon A, Khanduja S, Ziai W, Everett AD, Whitman G, Cho SM, On Behalf Of Herald Investigators. Brain injury plasma biomarkers in patients on veno-arterial extracorporeal membrane oxygenation: a pilot prospective observational study. Perfusion. Published online May 17, 2024. doi:10.1177/02676591241256006
Akbar AF, Rokui S, Zhou AL, Kilic A, King E, Cho SM. Incidence and risk factors for stroke after combined heart-kidney and heart-liver transplantation. Clin Transplant. 2024 Jun;38(6):e15369. doi: 10.1111/ctr.15369
Alexander PMA, Bembea MM, Cashen K, Cheifetz IM, Dalton HJ, Himebauch AS, Karam O, Moynihan KM, Nellis ME, Ozment C, Raman L, Rintoul NE, Said AS, Saini A, Steiner ME, Thiagarajan RR, Watt K, Willems A, Zantek ND, Barbaro RP, Steffen K, Vogel AM, Almond C, Anders MM, Annich GM, Brandão LR, Chandler W, Delaney M, DiGeronimo R, Emani S, Gadepalli SK, Garcia AV, Haileselassie B, Hyslop R, Kneyber MCJ, Baumann Kreuziger L, Le J, Loftis L, McMichael ABV, McMullan DM, Monagle P, Nicol K, Paden ML, Patregnani J, Priest J, Raffini L, Ryerson LM, Sloan SR, Teruya J, Yates AR, Gehred A, Lyman E, Muszynski JA; Pediatric ECMO Anticoagulation CollaborativE (PEACE), in collaboration with the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, the Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric ECMO subgroup of PALISI and the Extracorporeal Life Support Organization (PediECMO). Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE (PEACE) Consensus Conference. Pediatr Crit Care Med. 2024 Jul 1;25(7):643-675. doi: 10.1097/PCC.0000000000003480. Epub 2024 Jul 3.
Arbaje AI, Hsu YJ, Greyson S, Gurses AP, Marsteller J, Bowles KH, McDonald MV, Vergez S, Harbison K, Hohl D, Carl K, Leff B. Hospital-to-Home-Health Transition Quality (H3TQ) Index: further evidence on its validity and recommendations for implementation. Med Care. 2024 Aug 1;62(8):503-510. doi: 10.1097/MLR.0000000000002015
Azad TD, Stevens RD. Physiologic insults and individualized treatments in traumatic brain injury. Crit Care Med. 2024 Aug 1;52(8):1313-1317. doi: 10.1097/CCM.0000000000006327
Azamfirei R, Behrens D, Padilla S, Madden K, Goldberg S, Geno M, Manning MJ, Piole M, Madsen E, Maue D, Abu-Sultaneh S, Awojoodu R, Wang NY, Needham DM, Neufeld K, Kudchadkar SR. Delirium screening in critically ill children: secondary analysis of the multicenter PICU Up! pilot trial dataset, 2019-2020. Pediatr Crit Care Med. Published online June 4, 2024. doi:10.1097/PCC.0000000000003555
Azamfirei R, Procaccini D, Lobner K, Kudchadkar SR. The effects of intraoperative methadone on postoperative pain control in pediatric patients: a scoping review. Anesth Analg. 2024 Aug 1;139(2):263-271. doi: 10.1213/ANE.0000000000006548
Bass GA, Chang CWJ, Winkle JM, Cecconi M, Kudchadkar SR, Akuamoah-Boateng K, Einav S, Duffy CC, Hidalgo J, Rodriquez-Vega GM, Gandra-d’Almeida AJ, Barletta JF, Kaplan LJ. In-hospital violence and its impact on critical care practitioners. Crit Care Med. 2024;52(7):1113-1126. doi:10.1097/CCM.0000000000006189
Battaglini D, Kelly TL, Griffee M, Fanning J, Premraj L, Whitman G, Porto DB, Arora R, Thomson D, Pelosi P, White NM, Bassi GL, Suen J, Fraser JF, Robba C, Cho SM; COVID-19 Critical Care Consortium Investigators. Stroke in critically ill patients with respiratory failure due to COVID-19: disparities between low-middle and high-income countries. Heart Lung. 2024 Jul 4;68:131-144. doi: 10.1016/j.hrtlng.2024.06.015. Epub ahead of print.
Birdsong MT, Ascenzi J, Aquino C, Kudchadkar SR. Repositioning guidelines to decrease pressure injury in the pediatric intensive care unit: a quality improvement project. J Wound Ostomy Continence Nurs. 2024 Jul-Aug 01;51(4):271-275. doi: 10.1097/WON.0000000000001093. Epub 2024 Jul 19.
Casella JF, Furstenau DK, Adams RJ, Brambilla DJ, Lebensburger JD, Fehr JJ, Jordan LC, King AA, Ichord RN, McKinstry RC, Kraut MA, Shaw DW, White DA, Whyte-Stewart DA, Avadhani R, Barron-Casella EA, Cannon AD, Eaton CK, Riekert KA, Shay JE, Smith-Seidel CA, Weiss DC, Ostapkovich ND, Vermillion K, Treine KE, Kingsbury CE, Strouse JJ, Thompson RE, Hanley DF. Hydroxyurea to prevent brain injury in children with sickle cell disease (HU Prevent)-A randomized, placebo-controlled phase II feasibility/pilot study. Am J Hematol. 2024 Jul 2. doi: 10.1002/ajh.27423. Epub ahead of print.
Chinedozi ID, Boskamp E, Darby Z, Kang JK, Rando H, Sair H, Pitt J, Wilcox C, Kim BS, Khanduja S, Whitman G, Cho SM. Point-of-care bedside brain magnetic resonance imaging is safe in extracorporeal membrane oxygenation patients with swan ganz catheters: a phantom experiment and single center experience. J Surg Res. 2024;299:290-297. doi:10.1016/j.jss.2024.04.045
Choi UE, Nicholson RC, Frank SM, Cha S, Aziz H, Lester LC, Ariyo P, Cho BC, Hensley NB. Perioperative plasma in addition to red blood cell transfusions is associated with increased venous thromboembolism risk postoperatively. Anesth Analg. 2024 Aug 1;139(2):254-261. doi: 10.1213/ANE.0000000000006850. Epub 2024 Feb 28. PMID: 38416597. **Featured on the journal cover and accompanied by an editorial.
Choi UE, Nicholson RC, Thomas AJ, Crowe EP, Ulatowski JA, Resar LMS, Hensley NB, Frank SM. A propensity-matched cohort study of intravenous iron versus red cell transfusions for preoperative iron-deficiency anemia. Anesth Analg. 2024 Jul 22. doi: 10.1213/ANE.0000000000006974. Epub ahead of print. **Accompanied by an editorial.
Cinquegrana D, Boppana SH, Berman D, Nguyen TT, Baschat AA, Murphy J, Mintz CD. Anesthetic neurotoxicity in the developing brain: an update on theinsights and implications for fetal surgery. Anesth Pain Med. 2024 Jul 4. doi: 10.17085/apm.23128. Epub ahead of print.
Crisafi C, Grant MC, Rea A, Morton-Bailey V, Gregory AJ, Arora RC, Chatterjee S, Lother SA, Cangut B, Engelman DT; ERAS Cardiac Society Working Group. Enhanced Recovery After Surgery Cardiac Society turnkey order set for surgical-site infection prevention: proceedings from the American Association for Thoracic Surgery ERAS Conclave 2023. J Thorac Cardiovasc Surg. Published online April 3, 2024. doi:10.1016/j.jtcvs.2024.03.027
Cruz NC, Pham E, Ali H, Nanavati J, Steppan D, Kolb TM, Thomas AJ, Murphy J, Nyhan S, Grant MC, Steppan J. How severity and classification of pulmonary hypertension affect pregnancy outcomes: a systematic review and timeline. Int J Obstet Anesth. 2024 Aug;59:104210. doi: 10.1016/j.ijoa.2024.104210
Dalesio NM, Ullah MN, Lester L, Zaidi M, Chu R, Mendez A, Milnes V, Vaughn K, Hall K, Tunkel D, Kudchadkar SR, Walsh J. Preemptive airway management planning: a retrospective evaluation of the pediatric difficult airway consultation service. Acta Anaesthesiol Scand. 2024 Jul 24. doi: 10.1111/aas.14488. Epub ahead of print.
Feng CY, Kolchinski A, Kapoor S, Khanduja S, Hwang J, Suarez JI, Geocadin RG, Kim BS, Whitman G, Cho SM; HERALD Investigators. Prevalence and neurological outcomes of comatose patients with extracorporeal membrane oxygenation. J Cardiothorac Vasc Anesth. 2024 Jul 6:S1053-0770(24)00449-X. doi: 10.1053/j.jvca.2024.07.010. Epub ahead of print.
Feth M, Weaver N, Fanning RB, Cho SM, Griffee MJ, Panigada M, Zaaqoq AM, Labib A, Whitman GJR, Arora RC, Kim BS, White N, Suen JY, Li Bassi G, Peek GJ, Lorusso R, Dalton H, Fraser JF, Fanning JP; COVID-19 Critical Care Consortium. Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium. J Intensive Care. 2024;12(1):18. doi:10.1186/s40560-024-00726-2
Fowler CA, Ryder JM, Roberts AR, Sochet AA, Roddy MR. Methylprednisolone dosing for pediatric critical asthma: a single-center cohort study. J Asthma. 2024 Jul 6:1-7. doi: 10.1080/02770903.2024.2375276. Epub ahead of print.
Francoeur C, Alcamo AM, Robertson CL, Wainwright MS, Roa JD, Lovett ME, Stulce C, Yacoub M, Potera RM, Zivick E, Holloway A, Nagpal A, Wellnitz K, Even KM, Brunow de Carvalho W, Rodriguez IS, Schwartz SP, Walker TC, Campos-Miño S, Dervan LA, Geneslaw AS, Sewell TB, Pryce P, Silver WG, Lin JE, Vargas WS, Topjian A, McGuire JL, Domínguez Rojas JA, Tasayco-Muñoz J, Hong SJ, Muller WJ, Doerfler M, Williams CN, Drury K, Bhagat D, Nelson A, Price D, Dapul H, Santos L, Kahoud R, Appavu B, Guilliams KP, Agner SC, Walson KH, Rasmussen L, Pal R, Janas A, Ferrazzano P, Farias-Moeller R, Snooks KC, Chang CH, Iolster T, Erklauer JC, Jorro Baron F, Wassmer E, Yoong M, Jardine M, Mohammad Z, Deep A, Kendirli T, Lidsky K, Dallefeld S, Flockton H, Agrawal S, Siruguppa KS, Waak M, Gutiérrez-Mata A, Butt W, Bogantes-Ledezma S, Sevilla-Acosta F, Umaña-Calderón A, Ulate-Campos A, Yock-Corrales A, Talisa VB, Kanthimathinathan HK, Schober ME, Fink EL; Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID) Investigators. Severe pediatric neurological manifestations with SARS-CoV-2 or MIS-C hospitalization and new morbidity. JAMA Netw Open. 2024;7(6):e2414122. Published 2024 Jun 3. doi:10.1001/jamanetworkopen.2024.14122
Freedman L, Varughese A, Koirala B, Pandian V. Effectiveness of implementing a standardized perioperative pain management protocol in children undergoing tonsillectomy: a quality improvement project. Paediatr Anaesth. 2024 Aug;34(8):783-791. doi: 10.1111/pan.14917
Gao L, Skinner J, Nath T, Lin Q, Griffiths M, Damico RL, Pauciulo MW, Nichols WC, Hassoun PM, Everett AD, Johns RA. Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension. Respir Res. 2024;25(1):235. Published 2024 Jun 6. doi:10.1186/s12931-024-02861-8
Gilbertson LE, Muhly WT, Montana MC, Chidambaran V, DiCindio S, Sadacharam K, Wilder RT, Whyte SD, Hifko A, Sponseller PD, Frankville DD; North American Pediatric Spine Anesthesiologists Investigators. A survey of practice in the anesthetic management of adolescent idiopathic scoliosis spine fusion by the North American Pediatric Spine Anesthesiologists Collaborative. Paediatr Anaesth. 2024 Jul;34(7):645-653. doi: 10.1111/pan.14895
Haffar A, Hirsch A, Morrill C, Harris TGW, Crigger C, Garcia A, Maxon V, Di Carlo HN, Monitto C, Gearhart JP, Hunsberger JB. Perioperative management of primary classic bladder exstrophy: a single institutional pathway to success. J Pediatr Urol. 2024;20(3):406.e1-406.e7. doi:10.1016/j.jpurol.2024.01.010
Hanlon CE, Balmuri N, Vanderhoek SM. Perioperative care of the patient with a periodic fever syndrome. J Clin Anesth. 2024 Sep;96:111497. doi: 10.1016/j.jclinane.2024.111497
Hoyer EH, Bhave A, Xue W, Haut ER, Lau BD, Kraus P, Turnbull AE, Shaffer D, Friedman LA, Young D, Brotman DJ, Streiff MB. Inaccuracy of Initial Clinical Mobility Assessment in Venous Thromboembolism Risk Stratification. Am J Med. 2024 Aug;137(8):776-781. doi: 10.1016/j.amjmed.2024.04.003
Huang V, Roem J, Ng DK, McElrath Schwartz J, Everett AD, Padmanabhan N, Romero D, Joe J, Campbell C, Sigal GB, Wohlstadter JN, Bembea MM. Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO. Sci Rep. 2024;14(1):10790. doi:10.1038/s41598-024-61388-6
Hwang DY, Kim KS, Muehlschlegel S, Wartenberg KE, Rajajee V, Alexander SA, Busl KM, Creutzfeldt CJ, Fontaine GV, Hocker SE, Madzar D, Mahanes D, Mainali S, Sakowitz OW, Varelas PN, Weimar C, Westermaier T, Meixensberger J. Guidelines for neuroprognostication in critically ill adults with intracerebral hemorrhage. Neurocrit Care. 2024;40(2):395-414. doi:10.1007/s12028-023-01854-7
Jeong YH, Lim SK, Cho Y, Kim YJ, Jang HJ, Cho YH, Shin Y, Jung JS, Kang JK, Cho SM, Lee JH. Neuron-specific enolase as a predictor of neurologic outcomes in extracorporeal cardiopulmonary resuscitation patients. J Clin Med. 2024 Jul 15;13(14):4135. doi: 10.3390/jcm13144135
Jung D, Procaccini D, Roem J, Patel A, Ng DK, Bembea MM, Gobburu JVS. Pharmacokinetics of human plasma-derived antithrombin in pediatric patients supported on extracorporeal membrane oxygenation. J Clin Pharmacol. 2024 Jul 2. doi: 10.1002/jcph.2493. Epub ahead of print.
Karla A, Bachina P, Shou BL, Hwang J, Barshay M, Kulkarni S, Sears I, Eickhoff C, Bermudez CA, Brodie D, Ventetuolo CE, Whitman GLR, Abbasi A, Cho SM; HERALD Investigators. Utilizing machine learning to predict neurological injury in venovenous extracorporeal membrane oxygenation patients: an ELSO Registry analysis. JTCVS Open. 2024 Jul. doi: 10.1016/j.xjon.2024.06.013. Epub ahead of print.
Kalra A, Shou BL, Zhao D, Wilcox C, Keller SP, Kim BS, Whitman GJR, Cho SM; HERALD group. Extracorporeal membrane oxygenation physiological factors influence pulse oximetry and arterial oxygen saturation discrepancies. Ann Thorac Surg. 2024;117(6):1221-1228. doi:10.1016/j.athoracsur.2023.09.019
Kalra A, Wilcox C, Holmes SD, Tonna JE, Jeong IS, Rycus P, Anders MM, Zaaqoq AM, Lorusso R, Brodie D, Keller SP, Kim BS, Whitman GJR, Cho SM. Characterizing the racial discrepancy in hypoxemia detection in venovenous extracorporeal membrane oxygenation: an Extracorporeal Life Support Organization Registry analysis. Lung. Published online June 10, 2024. doi:10.1007/s00408-024-00711-4
Knol MJ, Poot RA, Evans TE, Satizabal CL, Mishra A, Sargurupremraj M, van der Auwera S, Duperron MG, Jian X, Hostettler IC, van Dam-Nolen DHK, Lamballais S, Pawlak MA, Lewis CE, Carrion-Castillo A, van Erp TGM, Reinbold CS, Shin J, Scholz M, Håberg AK, Kämpe A, Li GHY, Avinun R, Atkins JR, Hsu FC, Amod AR, Lam M, Tsuchida A, Teunissen MWA, Aygün N, Patel Y, Liang D, Beiser AS, Beyer F, Bis JC, Bos D, Bryan RN, Bülow R, Caspers S, Catheline G, Cecil CAM, Dalvie S, Dartigues JF, DeCarli C, Enlund-Cerullo M, Ford JM, Franke B, Freedman BI, Friedrich N, Green MJ, Haworth S, Helmer C, Hoffmann P, Homuth G, Ikram MK, Jack CR Jr, Jahanshad N, Jockwitz C, Kamatani Y, Knodt AR, Li S, Lim K, Longstreth WT, Macciardi F; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium; Mäkitie O, Mazoyer B, Medland SE, Miyamoto S, Moebus S, Mosley TH, Muetzel R, Mühleisen TW, Nagata M, Nakahara S, Palmer ND, Pausova Z, Preda A, Quidé Y, Reay WR, Roshchupkin GV, Schmidt R, Schreiner PJ, Setoh K, Shapland CY, Sidney S, St Pourcain B, Stein JL, Tabara Y, Teumer A, Uhlmann A, van der Lugt A, Vernooij MW, Werring DJ, Windham BG, Witte AV, Wittfeld K, Yang Q, Yoshida K, Brunner HG, Le Grand Q, Sim K, Stein DJ, Bowden DW, Cairns MJ, Hariri AR, Cheung CL, Andersson S, Villringer A, Paus T, Cichon S, Calhoun VD, Crivello F, Launer LJ, White T, Koudstaal PJ, Houlden H, Fornage M, Matsuda F, Grabe HJ, Ikram MA, Debette S, Thompson PM, Seshadri S, Adams HHH. Genetic variants for head size share genes and pathways with cancer. Cell Rep Med. 2024;5(5):101529. doi:10.1016/j.xcrm.2024.101529
Kobayashi RL, Gauvreau K, Alexander PMA, Teele SA, Fynn-Thompson F, Lasa JJ, Bembea M, Thiagarajan RR; American Heart Association’s (AHA) Get With The Guidelines-Resuscitation (GWTG-R) Investigators. Higher survival with the use of extracorporeal cardiopulmonary resuscitation compared with conventional cardiopulmonary resuscitation in children following cardiac surgery: results of an analysis of the Get With The Guidelines-Resuscitation Registry. Crit Care Med. 2024;52(4):563-573. doi:10.1097/CCM.0000000000006103
Lemon C, Rizer N, Bradshaw J. Climate change. Emerg Med Clin North Am. 2024 Aug;42(3):679-693. doi: 10.1016/j.emc.2024.02.022.
Leng A, Shou B, Liu O, Bachina P, Kalra A, Bush EL, Whitman GJR, Cho SM. Machine learning from veno-venous extracorporeal membrane oxygenation identifies factors associated with neurological outcomes. Lung. 2024 Aug;202(4):465-470. doi: 10.1007/s00408-024-00708-z
Linz MS, Booth LD, Milstone AM, Stockwell DC, Sick-Samuels AC. Evaluation of a comprehensive algorithm for picu patients with new fever or instability: association of clinical decision support with testing practices. Pediatr Crit Care Med. 2024 Jul 19. doi: 10.1097/PCC.0000000000003582. Epub ahead of print.
Lonsdale H, Rodriguez K, Shargo R, Ekblad M, Brown JM, Dolan I, Fierstein JL, Miller A, Dey A, Peck J, Rehman MA, Wilsey MJ. Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: a retrospective cohort study of 326 patients. Paediatr Anaesth. 2024 Jul;34(7):628-637. doi: 10.1111/pan.14888
Mahanes D, Muehlschlegel S, Wartenberg KE, Rajajee V, Alexander SA, Busl KM, Creutzfeldt CJ, Fontaine GV, Hocker SE, Hwang DY, Kim KS, Madzar D, Mainali S, Meixensberger J, Varelas PN, Weimar C, Westermaier T, Sakowitz OW. Guidelines for neuroprognostication in adults with traumatic spinal cord injury. Neurocrit Care. 2024;40(2):415-437. doi:10.1007/s12028-023-01845-8
McCrory MC, Akande M, Slain KN, Kennedy CE, Winter MC, Stottlemyre MG, Wakeham MK, Barnack KA, Huang JX, Sharma M, Zurca AD, Pinto NP, Dziorny AC, Maddux AB, Garg A, Woodruff AG, Hartman ME, Timmons OD, Heidersbach RS, Cisco MJ, Sochet AA, Wells BJ, Halvorson EE, Saha AK; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Social Determinants of Health Subgroup. Child Opportunity Index and pediatric intensive care outcomes: a multicenter retrospective study in the United States. Pediatr Crit Care Med. 2024;25(4):323-334. doi:10.1097/PCC.0000000000003427
Mercante A, Owens J, Bruni O, Nunes ML, Gringras P, Li SX, Papa S, Kreicbergs U, Wolfe J, Zernikow B, Lacerda A, Benini F; Pediatric Sleep and Palliative Care Group. International consensus on sleep problems in pediatric palliative care: paving the way. Sleep Med. 2024;119:574-583. doi:10.1016/j.sleep.2024.05.042
Millan PD, Kleiman AM, Friedman JF, Dunn LK, Gui JL, Bechtel AJ, Collins SR, Huffmyer JL, Dwivedi P, Wolpaw JT, Nemergut EC, Tsang S, Forkin KT. The impact of hindsight bias on the diagnosis of perioperative events by anesthesia providers: a multicenter randomized crossover study. J Clin Anesth. 2024 Jul 12;97:111549. doi: 10.1016/j.jclinane.2024.111549. Epub ahead of print.
Morais A, Imai T, Jin X, Locascio JJ, Boisserand L, Herman AL, Chauhan A, Lamb J, Nagarkatti K, Diniz MA, Kumskova M, Dhanesha N, Kamat PK, Badruzzaman Khan M, Dhandapani KM, Patel RB, Sutariya B, Shi Y, van Leyen K, Kimberly WT, Hess DC, Aronowski J, Leira EC, Koehler RC, Chauhan AK, Sansing LH, Lyden PD, Ayata C. Biological and procedural predictors of outcome in the stroke preclinical assessment network (span) trial. Circ Res. 2024 Jul 22. doi: 10.1161/CIRCRESAHA.123.324139. Epub ahead of print.
Moreno-Duarte I, Parikh RB, Paquin J, Steppan J, Spaeth JP, Nasr VG, Mittnacht AJC, Mossad EB. Selected 2023 highlights in congenital cardiac anesthesia. J Cardiothorac Vasc Anesth. 2024 Aug;38(8):1634-1640. doi: 10.1053/j.jvca.2024.03.034
Muehlschlegel S, Rajajee V, Wartenberg KE, Alexander SA, Busl KM, Creutzfeldt CJ, Fontaine GV, Hocker SE, Hwang DY, Kim KS, Madzar D, Mahanes D, Mainali S, Meixensberger J, Sakowitz OW, Varelas PN, Weimar C, Westermaier T. Guidelines for neuroprognostication in critically ill adults with moderate-severe traumatic brain injury. Neurocrit Care. 2024;40(2):448-476. doi:10.1007/s12028-023-01902-2
Muszynski JA, Bembea MM, Gehred A, Lyman E, Cashen K, Cheifetz IM, Dalton HJ, Himebauch AS, Karam O, Moynihan KM, Nellis ME, Ozment C, Raman L, Rintoul NE, Said A, Saini A, Steiner ME, Thiagarajan RR, Watt K, Willems A, Zantek ND, Barbaro RP, Steffen K, Vogel AM, Alexander PMA; Pediatric Extracorporeal Membrane Oxygenation (ECMO) Anticoagulation CollaborativE (PEACE), in collaboration with the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, the Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric ECMO subgroup of PALISI and the Extracorporeal Life Support Organization (PediECMO). Priorities for clinical research in pediatric extracorporeal membrane oxygenation anticoagulation from the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatr Crit Care Med. 2024 Jul 1;25(7 Suppl 1):e78-e89. doi: 10.1097/PCC.0000000000003488
Nair SS, Guo A, Boen J, Aggarwal A, Chahal O, Tandon A, Patel M, Sankararaman S, Durr NJ, Azad TD, Pirracchio R, Stevens RD. A deep learning approach for generating intracranial pressure waveforms from extracranial signals routinely measured in the intensive care unit. Comput Biol Med. 2024;177:108677. doi:10.1016/j.compbiomed.2024.108677
Nguyen M, Amanian A, Wei M, Prisman E, Mendez-Tellez PA. Predicting tracheostomy need on admission to the intensive care unit-a multicenter machine learning analysis. Otolaryngol Head Neck Surg. 2024 Jul 30. doi: 10.1002/ohn.919
Ott S, Lee ZY, Müller-Wirtz LM, Cangut B, Roessler J, Patterson W, Thomas CM, Bekele BM, Windpassinger M, Lobdell K, Grant MC, Arora RC, Engelman DT, Fremes S, Velten M, O’Brien B, Ruetzler K, Heyland DK, Stoppe C. The effect of a selenium-based anti-inflammatory strategy on postoperative functional recovery in high-risk cardiac surgery patients – A nested sub-study of the sustain CSX trial. Life Sci. 2024 Aug 15;351:122841. doi: 10.1016/j.lfs.2024.122841
Picetti E, Bouzat P, Bader MK, Citerio G, Helbok R, Horn J, Macdonald RL, McCredie V, Meyfroidt G, Righy C, Robba C, Sharma D, Smith WS, Suarez JI, Udy A, Wolf S, Taccone FS. A survey on monitoring and management of cerebral vasospasm and delayed cerebral ischemia after subarachnoid hemorrhage: the Mantra Study. J Neurosurg Anesthesiol. 2024;36(3):258-265. doi:10.1097/ANA.0000000000000923
Rae CD, Baur JA, Borges K, Dienel G, Díaz-García CM, Douglass SR, Drew K, Duarte JMN, Duran J, Kann O, Kristian T, Lee-Liu D, Lindquist BE, McNay EC, Robinson MB, Rothman DL, Rowlands BD, Ryan TA, Scafidi J, Scafidi S, Shuttleworth CW, Swanson RA, Uruk G, Vardjan N, Zorec R, McKenna MC. Brain energy metabolism: a roadmap for future research. J Neurochem. 2024;168(5):910-954. doi:10.1111/jnc.16032
Rintoul NE, McMichael ABV, Bembea MM, DiGeronimo R, Patregnani J, Alexander PMA, Muszynski JA, Steffen K, Gehred A, Lyman E, Cheifetz IM; Pediatric Extracorporeal Membrane Oxygenation (ECMO) Anticoagulation Collaborative (PEACE), in collaboration with the Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric ECMO subgroup of PALISI and the Extracorporeal Life Support Organization (PediECMO). Management of bleeding and thrombotic complications during pediatric extracorporeal membrane oxygenation: the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatr Crit Care Med. 2024 Jul 1;25(7 Suppl 1):e66-e77. doi: 10.1097/PCC.0000000000003489
Schwartz JM, Ng DK, Roem J, Padmanabhan N, Romero D, Joe J, Campbell C, Sigal GB, Wohlstadter JN, Everett AD, Bembea MM. Higher levels of brain injury biomarker tau are associated with unfavorable outcomes in patients supported with ECMO following cardiac arrest. Resusc Plus. 2024;18:100609. doi:10.1016/j.resplu.2024.100609
Shou BL, Kalra A, Zhou AL, Barbur I, McGoldrick MT, Larson E, Keller SP, Kim BS, Whitman GJR, Cho SM, Bush EL. Impact of extracorporeal membrane oxygenation bridging duration on lung transplant outcomes. Ann Thorac Surg. Published online May 11, 2024. doi:10.1016/j.athoracsur.2024.04.021
Steppan J, Wang H, Nandakumar K, Gadkari M, Poe A, Park L, Brady T, Berkowitz DE, Shimoda LA, Santhanam L. LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 Jul 16. doi: 10.1152/ajplung.00327.2023. Epub ahead of print.
Twichell S, Ashoor I, Boynton S, Dharnidharka V, Kizilbash S, Erez DL, Smith J; NAPRTCS Investigators. COVID-19 disease among children and young adults enrolled in the North American Pediatric Renal Trials and Collaborative Studies registry. Pediatr Nephrol. 2024;39(5):1459-1468. doi:10.1007/s00467-023-06241-0
Vanderhoek SM, Sklar MB, Zeng Y, Prichett LM, Wolf RM. Navigating advanced diabetes technologies in perioperative practice: a survey of pediatric anesthesiologists. Anesth Analg. 2024 Jul 12. doi: 10.1213/ANE.0000000000007039. Epub ahead of print.
Wahlster S, Sharma M, Taran S, Town JA, Stevens RD, Cinotti R, Asehnoune K, Robba C. Associations between driving pressure and clinical outcomes in acute brain injury: a subanalysis of ENIO. Am J Respir Crit Care Med. 2024;209(11):1400-1404. doi:10.1164/rccm.202402-0402LE
Wharton K, Chidiac C, Lopez C, Hunsberger J, Rhee D, Cappiello C, Garcia AV. Enhanced recovery after surgery 2.0: optimizing pain management in Nuss procedure: cryoablation and nerve block strategies for reduced opioid use. J Surg Res. 2024 Jul 24;301:563-571. doi: 10.1016/j.jss.2024.07.003. Epub ahead of print.
Willems A, Anders MM, Garcia AV, Vogel AM, Yates AR, Muszynski JA, Alexander PMA, Steffen K, Emani S, Gehred A, Lyman E, Raman L; Pediatric Extracorporeal Membrane Oxygenation [ECMO] Anticoagulation CollaborativE (PEACE), in collaboration with the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, the Pediatric Critical Care Blood Research Network (BloodNet), and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, and the Pediatric ECMO subgroup of PALISI and the Extracorporeal Life Support Organization (PediECMO). Management of Extracorporeal Membrane Oxygenation Anticoagulation in the Perioperative Period: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatr Crit Care Med. 2024 Jul 1;25(7 Suppl 1):e53-e65. doi: 10.1097/PCC.0000000000003490. Epub 2024 Jul 3.
Yakhkind A, Niznick N, Bodien YG, Hammond FM, Katz D, Luaute J, McNett M, Naccache L, O’Brien K, Schnakers C, Sharshar T, Slomine BS, Giacino JT; Curing Coma Campaign and its Contributing Members. Common data elements for disorders of consciousness: recommendations from the Working Group on Behavioral Phenotyping [published correction appears in Neurocrit Care. 2024 Feb;40(1):384. doi: 10.1007/s12028-023-01874-3]. Neurocrit Care. 2024;40(3):909-917. doi:10.1007/s12028-023-01844-9
Zhang Z, Zhang D, Lin Q, Cui X. Therapeutically fine-tuning autonomic nervous system to treat sepsis: a new perspective on the immunomodulatory effects of acupuncture. J Inflamm Res. 2024 Jul 5;17:4373-4387. doi: 10.2147/JIR.S477181
Zufer I, Fix RL, Stone E, Cane R, Sakran JV, Nasr I, Hoops K. Documentation of trauma-informed care elements for young people hospitalized after assault trauma. J Surg Res. 2024;296:665-673. doi:10.1016/j.jss.2024.01.030
Editorials and Commentaries
Brooks Peterson M, Yaster M, Lockman JL. The Pediatric Anesthesia Article of the Day (PAAD): A new solution to a ubiquitous problem. Paediatr Anaesth. 2024 Jul;34(7):589. doi: 10.1111/pan.14879
Frank SM, Hensley NB, Thomas AJ, Dawson CG, Resar LMS, Ulatowski JA, Crowe EP. Greater than sevenfold return on investment for a comprehensive patient blood management program with equivalent or improved outcomes. Anesth Analg. 2024;138(6):1345-1348. doi:10.1213/ANE.0000000000006862
Karri J, D’Souza RS, Wang EJ. Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs in the chronic kidney disease population: are they rational or reckless? Anesth Analg. 2024 Jul 1;139(1):235-237. doi: 10.1213/ANE.0000000000006574
Vost B, Poeran J, Carley M, Maalouf D. Letter to the editor regarding ‘Transitioning from intrathecal bupivacaine to mepivacaine for same-day discharge total joint arthroplasty: a quality improvement study’. Reg Anesth Pain Med. 2024 Jul 1:rapm-2024-105778. doi: 10.1136/rapm-2024-105778. Epub ahead of print.
Education and Training
Berman DJ, Schengel D. Common educational myths: separating the wheat from the chaff. ASA Monitor. 2024 Aug;88:e6. doi: 10.1097/01.ASM.0001027612.19798.86
Goeddel LA, Grant MC, Bandeen-Roche K, Vetter TR. Fortifying the evidence pyramid in anesthesiology and perioperative medicine: from cornerstone to capstone. Anesth Analg. 2024 Jul 15. doi: 10.1213/ANE.0000000000007032. Epub ahead of print.
Sampson JB, Koka R, Tomobi O, Chima A, Jackson EV, Rosen M, Koroma M, Nelson-Williams H, David E, Lee B. Bridging the mismatch: observing the introduction of new anesthesia technology for a low-resource environment. Front Med. 2024;11:1373593. Published 2024 May 2. doi:10.3389/fmed.2024.1373593
Winters BD. Rapid response systems. Crit Care Clin. 2024 Jul;40(3):583-598. doi: 10.1016/j.ccc.2024.03.008
Health Equity
Heidari O, Meyer D, Lowensen K, Patil A, O’Conor KJ, LaRicci J, Hunt D, Bocek AP, Cargill V, Farley JE. Colocating syringe services, COVID-19 vaccination, and infectious disease testing: Baltimore’s experience. Health Aff. 2024;43(6):883-891. doi:10.1377/hlthaff.2024.00032