“Integrative Extracellular Vesicle Transcriptomics: Towards a Liquid Biopsy for Chronic Diseases”
Presented by Visiting Professor and Keynote Speaker
Saumya Das, MD, PhD
Professor of Medicine at Harvard Medical School
Faculty member of the Cardiac Arrhythmia Service
Co-Director of the Inherited Arrhythmia Service at Massachusetts General Hospital
As director of Resynchronization and Advanced Cardiac Therapeutics Program, Dr. Das conducts research focused on the discovery and identification of RNA biomarkers in plasma that may prognosticate outcomes related to heart failure and arrhythmic events. A Mass General and Brigham and Women’s research team, led by Dr. Das, is currently validating a newly discovered set of RNA markers in over 4,000 patients as a part of a large-scale, NIH-funded study. Dr. Das hopes one day, certain sets of RNA markers might translate in the clinic as a test to help stratify patients based on risk for earlier and more definitive intervention.
Dr. Das has been the lead PI of several National Center for Advanced Translation (NCAT) grants to discover and validate RNA biomarkers of heart remodeling in heart failure. As part of the NIH Extracellular RNA Communication Consortium he has served as a co-chair of the steering committee. He was inducted in the American Society of Clinical Investigation in 2020 and also received an NIH EIA award (R35). He has served as a principal investigator on several American Heart Association strategic network grants, and is on the advisory board for American Association of Extracellular Vesicles. Work done in his laboratory has led to several patents. He is a cofounder of Long QT Therapeutics and Switch Therapeutics based on research done in his laboratory that seek to advance novel therapies for inherited arrhythmia syndromes and cardiac hypertrophy.
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Upcoming Grand Rounds
- 12/11/2025: Patient-Based Learning Discussion
- 12/18/2025: Quality Assurance Committee Meeting
- 12/25/2025: HOLIDAY – NO GRAND ROUNDS
- 1/1/2026: HOLIDAY – NO GRAND ROUNDS
- 1/8/2026: Visiting Professor Matthieu Legrand
- 1/15/2026: Patient-Based Learning Discussion
- 1/22/2026: Combined Grand Rounds: ACCM/Emergency Medicine