As part of the multidisciplinary structural heart team, Mary Beth Brady, MD FASE, Laeben Lester, MD and Benjamin Todd, MD staffed the inaugural case of transcatheter tricuspid valve replacement at Johns Hopkins. Saving lives everyday!
ACCM Achievements
September 2025
Thank you to everyone for sending in your announcements and pictures this month!
To view previous months newsletters, please follow the link below: https://anesthesiology.hopkinsmedicine.org/category/achievements/
Resident MVP Award Winners for Q1
It is our pleasure to announce the winners of the Resident MVP award for the first quarter of the academic year. Thank you to all the faculty who sent in nominations. It says a lot about our trainees that so many were suggested by their faculty for this award.
 Dr. Samip Patel CA3 class |  Dr. Chris Riis CA2 class |  Dr. Darby Moore CA1 class |
The award was established by generous gifts from appreciative ACCM attendings to recognize one resident in each class per quarter who goes above and beyond in their efforts to care for patients and to help support their colleagues. Thanks to the generous support of our faculty, the award comes with an honorarium for each resident.
The winners of this quarter’s MVP award are individuals who work incredibly hard, are always willing to stay late to help a colleague or volunteer to be there for anyone who needs it. They have volunteered their time outside of work to improve the program and always have positive can-do attitudes that lift the spirits of those around them.
Patient Blood Management Recertification Survey at JHH Concludes with No Citations, High Praise
We’re pleased to share that the Patient Blood Management (PBM) Recertification Survey at The Johns Hopkins Hospital, conducted Sept. 10, concluded with no citations.
This one-day visit, led by a single surveyor, included site visits to areas where blood is stored, administered, or transfused – such as the Adult Emergency Department, Blood Bank, OB/Labor & Delivery, SICU, Zayed 9W, and ZBOR 3 & 5. At each stop, the surveyor commended the dedication, passion, and stellar teamwork on display.
The surveyor praised the PBM and Bloodless Medicine Programs for their continued growth and excellence since first earning certification in 2017, stating, “Not another PBM-Bloodless program can rival what you do.” The surveyor also highlighted the strength of the program’s leadership in maintaining the highest standards of quality and performance.
Thank you to Dr. Steve Frank, Lisa Shifflett, and the Bloodless Medicine team for their leadership, and to Human Resources, the Medical Staff Office, Quality, Improvement, Transfusion Medicine, and Command Center staff for their support.
And thank you all for helping make this survey such a success.
Reminder: ACCM Applause is a place for us to celebrate our colleagues for the outstanding work they do every day. Do you know someone who deserves recognition? Click here to give them an Applause!
Student Nurse Anesthetists (SRNAs)
“Our student nurse anesthetists work very hard to be safe, efficient and ready to learn! They show up early with great attitudes and an eagerness to do well! They are valuable assets to our team! The SRNAs, with all their strengths and acquired knowledge will be caring for us in the future! Thank you SRNAs!!”
— Sarah Brown, CRNA
Darolyn Millburn
“I would like to put a Huge Shout Out to Darolyn Milburn for being recognized during the recent Executive Leadership Rounding on JHOC OR, her colleagues took time to recognize the exceptional care and support she brings to the team. Darolyn’s work and professionalism make a meaningful impact on both patients and staff. The leadership team recognized her for the work she does and for being someone the team knows they can rely on. Congratulations Darolyn!”
— Amy Schutter, CRNA
David Stockwell
“Dr. Stockwell, Thank you for your participation as a panelist on our selection committee for the inaugural Director of Advanced Practice Providers for The Johns Hopkins Hospital. Your thoughts and insights are invaluable.”
— Katy Hines, PA-C, MS, MBA – Executive Director for Advanced Practice, Johns Hopkins Medicine
ACCM Research Day
ACCM Research Day 2025 is just around the corner! We encourage the participation of all ACCM students, staff, residents, fellows, faculty members, and research personnel. Abstracts are due by 11:59pm October 17th 2025.
Submit your abstract: https://forms.office.com/r/4UuSCjHZ6V
This year’s faculty hosts, Joseph Walpole, MD PhD, and Sam Das, PhD, are excited to announce this year’s Visiting Professor, Saumya Das, MD PhD. Dr. Das is a Professor of Medicine at Harvard Medical School, a faculty member of the Cardiac Arrhythmia Service and the co-Director of the Inherited Arrhythmia Service at Massachusetts General Hospital. He serves as director of Resynchronization and Advanced Cardiac Therapeutics Program conducts research focused on the discovery and identification of RNA biomarkers in plasma that may prognosticate outcomes related to heart failure and arrhythmic events.
ACCOMPLISHMENTS AWARDS AND HONORS
Melania Bembea, MD, PhD, gave the Opening Plenary “Thriving as a Research-Driven Pediatric Intensivist” at the Clinical Research Course of the PALISI Research Network meeting held in Montreal, Canada. The PALISI meeting reunited Johns Hopkins alumni active in multiple areas of active research in pediatric critical care!
MaryBeth Brady with the ASE Interventional Echo council as well as the ASE president, Dr David Wiener. Mary Beth Brady MD FASE spoke at the American Society of Echocardiography Scientific Sessions in Nashville, TN on “Mitral Valve Edge-to-Edge Transcatheter Repair” and “Interventional Echo TED Talks: Where we are in 2025 and Tomorrow’s Vision! She serves as the chair-elect of the ASE’s Council on Interventional Echocardiography.
Phil Cohen, MD MSc and Sapna Kudchadkar, MD PhD were speakers at the Paediatric Critical Care Society Meeting in Belfast, UK in September. Dr. Cohen presented a long oral presentation on neonatologist and pediatric intensivist perspectives on NICU to PICU transfers, and Dr. Kudchadkar gave the closing keynote on 10 Years of PICU Up: Liberating the Critically Ill Child Together.
Marie Hanna, MD MEHP participated with 4 talks at the California Society of Anesthesiology in Hawaii: “Evidence base in medical Marijuana use”, “Pain treatment and regional anesthesia in ICU and trauma”, “Methadone and Suboxone treatment”, and “All you need to know about Upper and Lower extremity blocks”.
At this year’s International Ultrasonics Symposium (IEEE IUS 2025), 6 presentations featured Johns Hopkins faculty and staff:
Ananya Tandri, Yiyang You, Joseph Dardick, John Theodore, Dipankar Biswas, Mark Luciano, Jeeun Kang, “Novel ultrasound-Based Longitudinal Monitoring of Cerebrospinal Fluid Infection in shunt-Implanted Hydrocephalus Patients,” IEEE International Ultrasonics Symposium, 3637, Utrecht, The Netherlands, 2025.
Hyunwoo Song, Emad M. Boctor, Jeeun Kang, “Grating Lobe Suppression Using Synthetic Optically Tracked Sparse Aperture Focusing for Non-Contact Ultrasound Imaging,” IEEE International Ultrasonics Symposium, 3709, Utrecht, The Netherlands, 2025.
Jintan Zhang, Keshuai Xu, Laeben Lester, Emad Boctor, Jeeun Kang, Volumetric Vascular Access Guidance System with Sub-Millimeter Accuracy in Variable Ultrasound Orientations, IEEE International Ultrasonics Symposium, 3712, Utrecht, The Netherlands, 2025.
Keshaui Xu, Ananya Tandri, Mahban Gholijafari, Yunpu Zhang, Zeng-Jin Yang, Larraine Lage, Ernest M. Graham, Raymond C. Koehler, Emad M. Boctor, Jeeun Kang, Continuous Intrapartum Fetal Monitoring During Labor Using a Wearable Ultrasound and Photoacoustic Device: Proof-of-Concept Study in Vivo, IEEE International Ultrasonics Symposium, 3621, Utrecht, The Netherlands, 2025.
Yixuan Wu, Toshini Rajesh, Laetitia Saccenti, Mahban Gholijafari, Jeeun Kang, Jacob Enders, James Wiskin, Ayele Negussie, Lindsey Hazen, Sheng Xu, Baris Turkbey, Peter Pinto, Bradford J Wood, Emad Boctor, “Expanded 3D Digital Phantom Dataset of the Male Pelvis for Ultrasound and Photoacoustic Imaging,” IEEE International Ultrasonics Symposium, 3430, Utrecht, The Netherlands, 2025.
Yiyang You, Ananya Tandri, Emad M. Boctor, Youzuo Lin, Jeeun Kang, “NoGL-Net: a Deep Learning Approach to Grating Lobe Rejection Using Sparse RF Channel Interpolation in Synthetic Radial Aperture Focusing,” IEEE International Ultrasonics Symposium, 3620, Utrecht, The Netherlands, 2025.
Tymoteusz Kajstura, MD PhD won the American Society of Echocardiography travel scholarship award. Additionally, he took first place in the ASE’s CV Challenge with 70,843 steps!
Sapna Kudchadkar, MD, PhD received the Sean Berenholtz Award from the Armstrong Institute for Patient Safety and Quality at the 12th Annual JHM Quality, Safety and Service Summit on September 19th. This award was named in honor of Dr. Sean Berenholtz, esteemed professor in ACCM who helped found the Armstrong Institute and passed away in 2024. Dr. Berenholtz made an indelible mark on the field of patient safety, quality and service, and the award was created to honor colleagues who embody the values he modeled and applied in his everyday work as a person, colleague, mentor and healthcare provider. The award recognizes Dr. Kudchadkar’s leadership, mentorship, scholarship and unwavering commitment to improving healthcare safety and quality.
Johns Hopkins was well represented at this year’s Neurocritical Care Society (NCS) Meeting in Montreal, Quebec. The photos above capture 4 of the 14 posters presented by the JHU adult NCCU group at this year’s meeting along with the announcement of Dr. Susanne Muehlschegel’s appointment as Officer of the Board of Directors of the NCS.At this year’s Annual Meeting of the Neurocritical Care Society (NCS):
Dr. Jose Suarez moderated a session on “The Invisible Injury: Targeting Microvascular Dysfunction in Acute Brain Injury “, with talks by:
Dr. Vishank Sha: “Unraveling the Microcirculatory Puzzle: Mechanisms, Assessment, and Therapeutic Advances in Intracranial Hemorrhage”
Dr. Sung-Min Cho: “Breathing Life into ECMO: Unraveling the Impact of Oxygen, CO2, and Pulse Pressure on Cerebral Microcirculation”
And prior Hopkins NCCU fellow and faculty Dr. Lucia Rivera-Lara: “Breaking the Brain Barrier: Unraveling Cerebral Microcirculatory Dysfunction and Neuroinflammation in Sepsis and ARDS-associated Delirium”
Dr. Betsy Zink moderated a session on “Ethics and Recovery in Neurocritical Care: Addressing Barriers, Co-Survivorship, and Moral Responsibilities”
In addition to his session listed above, Dr. Sung-Min Cho also gave a talk on “Brain Resuscitation and Neuroprotection in Patients with ECPR”.
In addition to moderating the session listed above, Dr. Jose Suarez also gave a talk on “Communicating about Coma with Intensivists: Proceedings from the Brussels Consciousness Roundtable”.
After earning her M.D. from UVM’s Larner College of Medicine, Imelda Muller trained at the Naval Medical Center in San Diego and then entered a residency in anesthesia and critical care medicine at Johns Hopkins School of Medicine [which she completed this year]. At Hopkins, she became affiliated with the Human Spaceflight Lab, blending her clinical expertise with research into how human physiology adapts in space. https://vermontdailychronicle.com/uvm-trained-physician-joins-newest-nasa-astronaut-class/
Chelsey Santino, MD and Mary Beth Brady, MD FASE served as faculty at the Society of Thoracic Surgeons in Chicago, IL. Their station, Intraoperative TEE for Surgical Trainees, is the only station taught by non-surgical faculty.
Promotions and Appointments
Mary Beth Brady, MD FASE accepted the role of Chair of the American Society of Anesthesiologists’ Educational Track Subcommittee on Cardiac Anesthesiologists as well as the role of member on the Committee on Annual Meeting Oversight for the same Society.
Laura Chin, MD MPH, was appointed to both the Pediatric Anesthesia and Regional Anesthesia committees of the Society for Ambulatory Anesthesia.
Adam Laytin, MD MPH was accepted for fellowship in the American College of Critical Care Medicine.
Rashmi Prasad, MD was appointed to American Society of Anesthesiologist (ASA) 2026 Educational Track Subcommittee on Ambulatory Anesthesia and also has been appointed to a two-year term of ASA’s 2026 Committee on Patient Safety and Education.
Joseph Walpole, MD PhD was appointed to the role of Grand Rounds Activity Director for the Department of Anesthesiology and Critical Care Medicine.
ARTICLES PUBLISHED
Artificial Intelligence, Precision Medicine, and Machine Learning
Collins C, Fackler J, Sacco MJ, Jacobs M. Critical conversations: a user-centric approach to chatbots for history taking in the pediatric intensive care unit. Front Pediatr. 2025 Aug 12;13:1646989. doi: 10.3389/fped.2025.1646989. PMID: 40873736; PMCID: PMC12378061.
Harris C, Pimpalkar A, Aggarwal A, Yang J, Chen X, Schmidgall S, Rapuri S, Greenstein JL, Taylor CO, Stevens RD. Preoperative risk prediction of major cardiovascular events in noncardiac surgery using the 12-lead electrocardiogram: an explainable deep learning approach. Br J Anaesth. 2025 Sep 17:S0007-0912(25)00546-X. doi: 10.1016/j.bja.2025.07.085. Epub ahead of print. PMID: 40967934.
Moralez GM, Amado F, Liu VX, Tan SC, Meyfroidt G, Stevens RD, Pilcher D, Salluh JIF. Data-Driven Quality of Care in the ICU: A Concise Review. Crit Care Med. 2025 Sep 19. doi: 10.1097/CCM.0000000000006862. Epub ahead of print. PMID: 40970767.
Winter MC, Zhou AX, Laksana E, Aczon MD, Ledbetter DR, Avesar M, Burkiewicz K, Chandnani HK, Fainberg N, Hsu S, McCrory MC, Morrow KR, Noguchi A, O’Brien CE, Ojha A, Pringle C, Ross PA, Shah J, Shah S, Shpaner L, Siegel LB, Tripathi S, Wetzel RC; Pediatric Data Science and Analytics (PEDAL) subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Death One Hour After Terminal Extubation in Children: Validation of a Machine Learning Model to Predict Cardiac Death After Withdrawal of Life-Sustaining Treatment in a Multicenter Cohort, 2009-2021. Pediatr Crit Care Med. 2025 Aug 1;26(8):e997-e1008. doi: 10.1097/PCC.0000000000003772. Epub 2025 Jun 25. PMID: 40558604.
Basic and Translational Research
Acter S, Lin Q. S100 proteins as a key immunoregulatory mechanism for NLRP3 inflammasome. Front Immunol. 2025 Aug 28;16:1663547. doi: 10.3389/fimmu.2025.1663547. PMID: 40948742; PMCID: PMC12422935.
Boisserand LSB, Herman AL, Sanganahalli BG, Mihailovic J, Beatty HE, Johnson CW, Diaz S, DeLong JH, Velazquez S, Grutzendler J, Dela Cruz C, Zhou J, Sheth KN, Matouk C, Zhan S, Morais A, Imai T, Chauhan A, Patel RB, Kumskova M, Shi Y, Avery BD, Lamb J, Nagarkatti KA, Khan MB, Kamat PK, Dhandapani KM, McCullough LD, Aronowski J, Hess D, Koehler RC, Lyden P, Leira EC, Chauhan AK, Ayata C, Chen MH, Diniz MA, Hyder F, Sansing LH; SPAN investigators. Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network. Stroke. 2025 Sep 3. doi: 10.1161/STROKEAHA.125.050903. Epub ahead of print. PMID: 40899256.
Fernandez RF, Weglarczyk P, Zokaei S, Huguenin S, Scafidi J, Ellis JM, Scafidi S. Aging Effects on Lipid Metabolism in Response to Traumatic Brain Injury. J Neurochem. 2025 Sep;169(9):e70227. doi: 10.1111/jnc.70227. PMID: 40939097; PMCID: PMC12431718.
Gok O, Sharma A, Kambhampati SP, Smith Khoury E, Kannan S, Kannan RM. Sustained and Step-Wise Drug Release by a Novel Double Responsive Dendrimer-N-Acetylcysteine Conjugate. Biomacromolecules. 2025 Jul 14;26(7):4274-4285. doi: 10.1021/acs.biomac.5c00283. Epub 2025 Jul 3. PMID: 40605647.
Hwang H, Sarkar C, Piskoun B, Zhang N, Borcar A, Robertson CL, Lipinski MM, Yadava N, Goodfellow MJ, Polster BM. Idebenone Enhances the Early Microglial Response to Traumatic Brain Injury and Mitigates Acute Gene Expression Changes to Ephrin-A and Dopamine Signaling Pathways. bioRxiv [Preprint]. 2025 May 11:2025.05.06.652467. doi: 10.1101/2025.05.06.652467. Update in: Cells. 2025 Jun 01;14(11):824. doi: 10.3390/cells14110824. PMID: 40654680; PMCID: PMC12247630.
Israel MR, Berwick R, Vastani N, Zheng Q, Moore W, Maurer M, Gentry C, Marshall A, Sun H, Neiland H, Dunham J, Bouchatta O, Plant K, Nagi SS, Olausson H, Alam U, Dong X, Bevan S, Marshall A, Goebel A, Andersson DA. Aβ low threshold mechanoreceptors contribute to sensory abnormalities in fibromyalgia. Brain. 2025 Sep 3:awaf321. doi: 10.1093/brain/awaf321. Epub ahead of print. PMID: 40898777.
Jiang B, Graham E, Unberath M, Taylor RH, Koehler RC, Kang J, Boctor EM. Automatic photoacoustic monitoring of perinatal brain hypoxia with superior sagittal sinus detection. J Biomed Opt. 2025 Jul;30(7):076004. doi: 10.1117/1.JBO.30.7.076004. Epub 2025 Jul 11. PMID: 40655941; PMCID: PMC12245645.
Jin X, Morais A, Imai T, Lamb J, Nagarkatti K, Boisserand L, Beatty HE, Sansing LH, Khan MB, Dhandapani K, Kamat P, Hess DC, Patel RB, Kumskova M, Chauhan AK, McCullough LD, Aronowski J, Leira EC, Shi Y, Avery BD, Koehler RC, Lyden PD, Ayata C. Determinants of Outcome After Endovascular Middle Cerebral Artery Occlusion in Rats in the SPAN Trial. Stroke. 2025 Sep;56(9):2734-2747. doi: 10.1161/STROKEAHA.125.051235. Epub 2025 May 21. PMID: 40396268; PMCID: PMC12353655.
Porras T, Cao M, Briscoe J, Kang JK, Chinedozi ID, Darby Z, Khanduja S, Bezerianos A, Thakor N, Whitman G, Mukherjee D, Keller S, Cho SM. Investigating the dynamics of intracranial pressure and cerebral autoregulation during extracorporeal cardiopulmonary resuscitation using a porcine model. Resusc Plus. 2025 Jun 16;25:101003. doi: 10.1016/j.resplu.2025.101003. PMID: 40611828; PMCID: PMC12226061.
Rohn MCH, Simeone JM, Doctorman S, Ge P, Hernandez A, Das S, Spann M, Dow M, Segars J, Singh B. The Functional Role of Cumulus Cells and Their Influence on Oocyte Quality: A Systematic Review. Reprod Sci. 2025 Sep;32(9):2877-2902. doi: 10.1007/s43032-025-01940-5. Epub 2025 Aug 6. PMID: 40768027.
Scafidi S, Xu S, Jernberg JN, Chu T, Fiskum G, McKenna MC. Longitudinal Brain Structural, Neurochemical, and Behavioral Changes Following Traumatic Brain Injury in Immature Rat Brain with ALCAR Treatment. Neurochem Res. 2025 Jul 30;50(4):256. doi: 10.1007/s11064-025-04494-9. PMID: 40736608; PMCID: PMC12310762.
Song Z, Wang X, Zeng J, Ren F, Wang Y, Li M, Lin Q, Li W, Liao X, Wang D. DHA and EPA exacerbate hypoxia-induced ferroptosis in gastric and small intestinal mucosa by disrupting the balance between SLC7A11 upregulation and PUFA-PL accumulation. J Lipid Res. 2025 Sep;66(9):100876. doi: 10.1016/j.jlr.2025.100876. Epub 2025 Aug 12. PMID: 40812725; PMCID: PMC12450627.
Steger L, Ghaith AK, Weber-Levine C, Robinson K, Krueger C, Smit C, Krishnan S, Leadingham KMK, Davidar D, Routkevitch D, Jiang K, Quiroz V, Bauer S, Liang R, Kerensky M, Suk I, Tyler B, Doloff JC, Theodore N, Manbachi A. Precision in Spinal Cord Injury Research: A Novel Electromagnetic Impactor for a Consistent Porcine Model. Ann Biomed Eng. 2025 Sep 5. doi: 10.1007/s10439-025-03836-6. Epub ahead of print. PMID: 40913214.
Clinical Research
Batra D, Chen M, Meis J, Möhlenbruch MA, Klose C, Ringleb P, Shah V, Bösel J, Schönenberger S. Feasibility of non-invasive neuromonitoring using BIS and NIRS during endovascular treatment of acute ischemic stroke. Neurol Res Pract. 2025 Aug 26;7(1):60. doi: 10.1186/s42466-025-00420-0. PMID: 40859303; PMCID: PMC12382210.
Bradshaw J, Lung S, Shrestha G. A Woman With Dyspnea and Dysphonia. Ann Emerg Med. 2025 Sep;86(3):286-287. doi: 10.1016/j.annemergmed.2025.03.010. PMID: 40846429.
Cohen PD, Schultz BRE, Schuette J, Kudchadkar SR. N-Acetylcysteine and Hemodialysis in Severe Acetaminophen Toxicity in a 15-Year-Old Adolescent: A Case Report. Am J Case Rep. 2025 Aug 12;26:e948715. doi: 10.12659/AJCR.948715. PMID: 40794548; PMCID: PMC12357520.
Crockett CJ, Szolnoki J, Khan S, Lee AC, Kaizer A, Olomu P, Peterson MB; Pediatric Difficult Intubation Collaborative. Paediatric difficult intubations and the impact of timing of weekend versus weekday cases: an analysis of the Pediatric Difficult Intubation registry. Br J Anaesth. 2025 Aug 18:S0007-0912(25)00447-7. doi: 10.1016/j.bja.2025.07.033. Epub ahead of print. PMID: 40829974.
Demir ZA, Kavak Akelma F, Akça O, Koltka K, Dinçer B, Kocyigit M, Tuna AT, Sayın J, Yıldırım Ar A, Kuvaki B, Aykut A, Sahin AS, Aydın Güzey N; ADEFES Investigators. Impact of fibrinogen-to-erythrocyte suspension ratio on mortality and functional outcomes in major perioperative bleeding (Approximate Dose-Equivalent of Fibrinogen-to-Erythrocyte Suspension (ADEFES) study): protocol for a prospective observational study. BMJ Open. 2025 Sep 16;15(9):e099044. doi: 10.1136/bmjopen-2025-099044. PMID: 40962355; PMCID: PMC12443187.
Doré KJ, Kelly CM, Cornell TT, Rasmussen LK, Burk S, Loftis LL, Allen C, Bembea MM, Boville BM, Furlong-Dillard J, Kaipa S, Norton B, Viamonte H, Wallenkamp L, Said A, Steiner ME, Malone MP, Kline A, Tawfik D. Temporal trends and risk factors for bleeding and thrombosis in pediatric ECMO: A multicenter cohort study. Perfusion. 2025 Jul 31:2676591251365417. doi: 10.1177/02676591251365417. Epub ahead of print. PMID: 40741691.
Goeddel LA, Hernandez M, Koffman L, Santino C, Muschelli J 3rd, Zhou X, Waldron N, Parikh CR, Lester L, Abozaid R, Faraday N, Crainiceanu CM, Brown C 4th. Assessment of Renal Vein Flow Index by Transesophageal Echocardiography: Precision, Variability, and Association with Cardiac Index During Cardiac Surgery. J Cardiothorac Vasc Anesth. 2025 Sep;39(9):2307-2314. doi: 10.1053/j.jvca.2025.05.052. Epub 2025 May 29. PMID: 40541473; PMCID: PMC12228528.
Hwang J, Johnson EL, Cho SM, Geocadin R, Habela CW, Ritzl EK. Granularity of EEG reactivity in response to stimulation: “Atypical” reactivity in non-sedated and sedated patients. Clin Neurophysiol. 2025 Aug 31;179:2110996. doi: 10.1016/j.clinph.2025.2110996. Epub ahead of print. PMID: 40945234.
Kalra A, Kang JK, Wilcox C, Brown P, Ritzl E, Bavaria JE, Zaaqoq AM, Brodie D, Whitman GJR, Cho SM. Incidence, Risk Factors, and Outcomes of Seizures in Extracorporeal Cardiopulmonary Resuscitation Patients: An Analysis of the Extracorporeal Life Support Organization Registry. ASAIO J. 2025 Aug 22. doi: 10.1097/MAT.0000000000002532. Epub ahead of print. PMID: 40844149.
Kang JK, Kim J, Chung H, Kalra A, Khanduja S, Darby ZE, Chinedozi ID, Briscoe JB, Kim BS, Whitman GJR, Cho SM; HERALD Investigators. Impact of Obesity on Neurologic Outcomes in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. 2025 Sep;39(9):2369-2376. doi: 10.1053/j.jvca.2025.05.029. Epub 2025 May 22. PMID: 40518336.
Liu WL, van Gelderen E, Mawalkar R, Wang EJ, Treisman G, Cohen SP. Do difficult encounters affect pain treatment outcomes? A prospective cohort study. Pain Med. 2025 Sep 1;26(9):554-561. doi: 10.1093/pm/pnaf027. PMID: 40100641.
Nelson SE, Weiner C, Hua J, Sair HI, Suarez JI, Stevens RD. Connectome reorganization and functional recovery after subarachnoid hemorrhage. J Stroke Cerebrovasc Dis. 2025 Sep;34(9):108406. doi: 10.1016/j.jstrokecerebrovasdis.2025.108406. Epub 2025 Jul 23. PMID: 40712956.
Nepogodiev D, Picciochi M, Ademuyiwa A, Adisa A, Agbeko AE, Aguilera ML, Agyei F, Alexander P, Henry J, Anyomih TTK, Aregawi AB, Atun R, Biccard B, Chalwe M, Chu K, Coomarasamy A, Crawford R, Darzi A, Davies J, Gathuya Z, George C, Ghaffar A, Ghosh D, Glasbey JC, Haque PD, Harrison EM, Hesse A, Allen Ingabire JC, Kamarajah SK, Karekezi C, Kruger D, Lapitan MC, Latif A, Lawani I, Ledda V, Li E, Linder C, Makasa E, Martin J, Maswime S, Mathai S, Meara JG, Mudede-Moffat F, Ntirenganya F, Park KB, Phelan LN, Pramesh CS, Ramos-De la Medina A, Raykar N, Rivello R, Roslani AC, Roy N, Samad L, Shrime M, Sobhy S, Sullivan R, Tabiri S, Tangi V, Tissingh E, Weiser TG, Williams O, Bhangu A. Surgical health policy 2025-35: strengthening essential services for tomorrow’s needs. Lancet. 2025 Aug 23;406(10505):860-880. doi: 10.1016/S0140-6736(25)00985-7. Epub 2025 Jul 14. Erratum in: Lancet. 2025 Sep 20;406(10509):1222. doi: 10.1016/S0140-6736(25)01866-5. PMID: 40675172.
Nyhan SM, Gadkari M, Brady T, Martinez Yus M, Choi R, Bauer M, Vithani S, Walpole J, Hays AG, Aziz H, Kilic A, Robich M, Gammie JS, Santhanam L, Steppan J. Preoperative serum LOXL2 levels are elevated in patients with pulmonary hypertension undergoing mitral valve surgery in a prospective observational cohort study. J Appl Physiol (1985). 2025 Aug 1;139(2):325-333. doi: 10.1152/japplphysiol.00287.2025. Epub 2025 Jul 10. PMID: 40637430; PMCID: PMC12320476.
Ruiz-Gonzalez CE, Nino-Meza OJ, Singh M, Masias-Leon Y, Kronenberg A, Shambles M, Chen X, Tucker EW, Lodge MA, Carroll LS, Cooke KR, Kates OS, Shoham S, Zhang SX, Jain SK. 18F-Fluorodeoxysorbitol PET for noninvasive detection of invasive mold infections: preclinical and first-in-human studies. Nat Commun. 2025 Jul 10;16(1):6395. doi: 10.1038/s41467-025-61700-6. PMID: 40640182; PMCID: PMC12246407.
Sollmann M, Bode LM, Krämer S, Lacher M, Müller SD, Breidenbach S, Greul F, Zimmermann P, Piegeler T. Superior recovery and efficiency with laryngeal mask airway compared to endotracheal intubation in minimally invasive repair of pectus excavatum: a retrospective analysis. BMC Anesthesiol. 2025 Sep 1;25(1):438. doi: 10.1186/s12871-025-03320-7. PMID: 40890592; PMCID: PMC12400620.
Thomas AJ, Adegboye J, Myers E, Sekaran A, Choi UE, Christian J, Hendricks EA, Stanislaus M, Murphy JD, Eke A, Vaught AJ, Resar LMS, Frank SM. Management strategies and clinical outcomes of obstetric patients who decline allogeneic blood transfusion. Vox Sang. 2025 Sep;120(9):904-912. doi: 10.1111/vox.70061. Epub 2025 Jun 10. PMID: 40494754.
Vallabhaneni N, Jaffray J, Branchford BR, Betensky M, Stillings A, Krava E, Alleyne MM, Ashour D, Goldenberg NA, Sochet AA. Thromboprophylaxis for Critically Ill Adolescents: A Multicenter Case-Control Study From the Children’s Healthcare Advancements in Thrombosis Consortium. Pediatr Crit Care Med. 2025 Sep 1;26(9):e1126-e1137. doi: 10.1097/PCC.0000000000003788. Epub 2025 Jul 2. PMID: 40601352.
Vattipally VN, Aude CA, Ran KR, Das O, Giwa GA, Rincon-Torroella J, Xu R, Byrne JP, Muehlschlegel S, Suarez JI, Mukherjee D, Huang J, Azad TD, Bettegowda C. Care intensity associated with sociodemographic factors without influencing inpatient mortality for patients with severe traumatic brain injury receiving palliative care. J Clin Neurosci. 2025 Sep;139:111479. doi: 10.1016/j.jocn.2025.111479. Epub 2025 Jul 12. PMID: 40652890.
Vattipally VN, Ran KR, Rajan AP, Jo J, Suarez JI, Sakran JV, Haut ER, Huang J, Bettegowda C, Azad TD. Incarceration Status is Associated With Rates of Operative Neurosurgical Intervention and Inpatient Mortality After Traumatic Brain Injury. Neurosurgery. 2025 Sep 18. doi: 10.1227/neu.0000000000003746. Epub ahead of print. PMID: 40965210.
Wiegand JL, Thompson JA, Landeck BF, Fierstein JL, Ashour D, Machry JS, Kiskaddon AL, Betensky M, Freire GA. Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease. Pulm Circ. 2025 Sep 10;15(3):e70164. doi: 10.1002/pul2.70164. PMID: 40948578; PMCID: PMC12423430.
Ziai WC, Yarava A, Gruber JB, Li Y, Walborn N, Rizzutti N, Hildreth M, Awad I, Hanley DF. Impact of Minimally Invasive Surgery on Midline Shift and Outcomes in Large Supratentorial Spontaneous Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE III. Neurocrit Care. 2025 Sep 16. doi: 10.1007/s12028-025-02371-5. Epub ahead of print. PMID: 40958054.
Editorials, Literature Reviews and Technical Guides
Ayata C, Bath PM, Planas AM, Allan SM, Boltze J, Cabeen RP, Gibson CL, Cipolla MJ, Diniz MA, Fumagalli S, Hyder F, Koehler RC, Liesz A, McCann SK, Magnus T, McCullough LD, Sena ES, Beretta S, Aronowski J, Bosetti F, Wright CB, Lyden PD, Sansing LH. Preclinical Ischemic Stroke Multicenter (PRISM) Trials Collective Statement: Opportunities, Challenges, and Recommendations for a New Era. Stroke. 2025 Sep 11:10.1161/STROKEAHA.125.052056. doi: 10.1161/STROKEAHA.125.052056. Epub ahead of print. PMID: 40931817; PMCID: PMC12455296.
Chernishof V, Nour S, Chen SE, Na YB, Prichett L, Vanderhoek SM. Safe Selection: A Multi-Center Analysis of Exclusion Criteria in Pediatric Ambulatory Surgery Centers. Paediatr Anaesth. 2025 Aug 14. doi: 10.1111/pan.70037. Epub ahead of print. PMID: 40810702.
Cossu AE, Goswami DK, Faraoni D, Downey LA. Establishing Pediatric Patient Blood Management Programs: A Path Worth Pursuing? Anesth Analg. 2025 Sep 1;141(3):545-549. doi: 10.1213/ANE.0000000000007501. Epub 2025 Apr 4. PMID: 40184311.
Durr KM, Tropiano J, Rochwerg B, Fernando SM, Carrier M, Siegal DM, Rosenkrantz L, Haut ER, Dawe P, Joos E, Garraway N, Hawes H, Glen P, Matar M, Lampron J, Stuleanu T, Tran A. Randomized Controlled Trials for the Prevention of Venous Thromboembolism in Trauma and Emergency General Surgery Patients: A Systematic Review of Sample Size Methodologies. J Surg Res. 2025 Aug 25;314:559-566. doi: 10.1016/j.jss.2025.07.053. Epub ahead of print. PMID: 40857867.
Kemper E, Fackler J. The Time is Now. Pediatr Crit Care Med. 2025 Aug 1;26(8):e1060-e1062. doi: 10.1097/PCC.0000000000003787. Epub 2025 Jul 1. PMID: 40590638.
Mintz CD, Vutskits L. Neural Network Dynamics of Postoperative Delirium: Is It All about Neurons Striking the Right Balance? Anesthesiology. 2025 Sep 1;143(3):496-498. doi: 10.1097/ALN.0000000000005610. Epub 2025 Aug 12. PMID: 40793801.
Tomobi O, Sampson J, Johnstone R, Hayanga HK. History of the preanesthesia evaluation: Appreciating the tensions in the anesthesiologist-patient relationship. J Natl Med Assoc. 2025 Sep 18:S0027-9684(25)00308-6. doi: 10.1016/j.jnma.2025.08.112. Epub ahead of print. PMID: 40973542.
Vost B, Poeran J, Carley M, Maalouf D. Letter to the editor regarding ‘Transitioning from intrathecal bupivacaine to mepivacaine for same-day discharge total joint arthroplasty: a quality improvement study’. Reg Anesth Pain Med. 2025 Sep 4;50(9):768. doi: 10.1136/rapm-2024-105778. PMID: 38955398.
Education and Quality Improvement
Abdullah S, Ku JB, Sutton O, Gill J, Yong RJ, Viswanath O, Robinson CL, Hasoon J. Practice Patterns and Perspectives on Epidural Steroid Injections by Interventional Pain Physicians. Pain Ther. 2025 Sep 19. doi: 10.1007/s40122-025-00772-0. Epub ahead of print. PMID: 40971109.
Brigham EM, Hodgman EI, Shilkofski NA, Jeffers JM, An D, Tackett S, Nasr IW, Levin AB. Improving pediatric trauma care at a level 1 pediatric trauma center through the multi-year implementation of a Pediatric Trauma Boot Camp curriculum. Adv Simul (Lond). 2025 Jun 17;10(1):34. doi: 10.1186/s41077-025-00363-1. PMID: 40528249; PMCID: PMC12175439.
Cohen PD, Gontasz MM, Bernier M, Zaniletti I, Kudchadkar SR, Sochet AA, Stockwell DC. Intrafacility Neonatal Intensive Care Unit to Pediatric Intensive Care Unit Transfer in the United States: A Pediatric Health Information Systems Registry Study. J Pediatr Clin Pract. 2025 Jun 6;17:200154. doi: 10.1016/j.jpedcp.2025.200154. PMID: 40607443; PMCID: PMC12221531.
Hasoon J, Chung M, Yazdi C, Robinson CL. Evaluation of Landmark-Based and Fluoroscopic-Guided Sacroiliac Joint Injections-A Pilot Series. Orthop Rev (Pavia). 2025 Aug 20;17:143090. doi: 10.52965/001c.143090. PMID: 40860249; PMCID: PMC12372924.
Kaufman M, Jahr JS, Klompas AM, Perelman S, Raphael J, Tan GM, Frank SM, Waters JH, Warner MA. Exploring Myths of Perioperative Autologous Red Blood Cell Salvage. Anesthesiology. 2025 Sep 15:10.1097/ALN.0000000000005586. doi: 10.1097/ALN.0000000000005586. Epub ahead of print. PMID: 40951985; PMCID: PMC12440369.
Kislik G, Fox R, Korotcov AV, Zhou J, Febo M, Moghadas B, Bibic A, Zou Y, Wan J, Koehler RC, Adebayo T, Burns MP, McCabe JT, Wang KK, Huie JR, Ferguson AR, Paydar A, Wanner IB, Harris NG; TOP-NT Investigators. Improved injury detection through harmonizing multi-site neuroimaging data after experimental TBI: a Translational Outcomes Project in Neurotrauma consortium study. Front Neurol. 2025 Aug 20;16:1612598. doi: 10.3389/fneur.2025.1612598. PMID: 40909007; PMCID: PMC12406496.
Naureckas Li C, Blumenthal JA, Sick-Samuels AC. Use and Stewardship of Molecular Testing for Diagnosis of Infectious Diseases: A Cross-Sectional Survey. J Pediatric Infect Dis Soc. 2025 Aug 27;14(8):piaf065. doi: 10.1093/jpids/piaf065. PMID: 40720778; PMCID: PMC12363072.
Zhang N, Roelofs BA, Bordt EA, Piskoun B, Robertson CL, Polster BM. CRABS-ROC, A respirometry protocol for overcoming substrate limitations, reveals excess brain mitochondrial Complex I capacity. Free Radic Biol Med. 2025 Sep 9;241:24-31. doi: 10.1016/j.freeradbiomed.2025.09.011. Epub ahead of print. PMID: 40935348.
Health Environment and Equity
Greene JA, Merritt MW, Paina L, Bucic SB, Dalesio N, Hanley C, Mediate E, Wadhwa S, Alfonzo Horowitz M, Gately UE, Tharp M, Singh H; PASS-UP Working Group. A Pragmatic Approach to Streamlining Single-Use Plastics in Health Care. Ann Intern Med. 2025 Aug;178(8):1192-1194. doi: 10.7326/ANNALS-25-01264. Epub 2025 Jun 24. PMID: 40550138.
Lazar A, Froyshteter AB, Holman AE, Whitaker EE. Perspectives on Starting a Pediatric Spinal Anesthesia Program. Paediatr Anaesth. 2025 Sep;35(9):716-724. doi: 10.1111/pan.15141. Epub 2025 Jun 10. PMID: 40492545.
McCrory MC, Saha AK, Rogerson CM, Grunwell JR, Kennedy CE, Winter MC, Wakeham MK, Zurca AD, Dziorny AC, Maddux AB, Hartman ME, Pinto NP, Huang JX, Sharma M, Barnack KA, Garg A, Akande MY. Child Opportunity Index and Outcomes of Children Admitted to US PICUs for Critical Asthma. Pediatr Pulmonol. 2025 Sep;60(9):e71309. doi: 10.1002/ppul.71309. PMID: 41001938.
Suleman MI, Essuman AA, Dada M, Williams K. The Johns Hopkins multidisciplinary pediatric pain management service: a concept paper. Pain Manag. 2025 Sep;15(9):587-593. doi: 10.1080/17581869.2025.2532356. Epub 2025 Jul 13. PMID: 40653781.